Associations of the circulating levels of cytokines with risk of amyotrophic lateral sclerosis: a Mendelian randomization study

Associations of the circulating levels of cytokines with risk of amyotrophic lateral sclerosis: a Mendelian randomization study

Abstract Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that is accompanied by muscle weakness and muscle atrophy, typically resulting in death within 3–5 years from the disease occurrence. Though the cause of ALS remains unclear, increasing evidence has suggested tha...

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Bibliographic Details
Main Authors: Bin Liu, Linshuoshuo Lyu, Wenkai Zhou, Jie Song, Ding Ye, Yingying Mao, Guo-Bo Chen, Xiaohui Sun
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Medicine
Subjects:
Amyotrophic lateral sclerosis
Cytokine
Genome-wide association study
Mendelian randomization
Single nucleotide polymorphisms
Online Access:https://doi.org/10.1186/s12916-023-02736-7

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