Implications of epithelial-mesenchymal plasticity for heterogeneity in colorectal cancer

Implications of epithelial-mesenchymal plasticity for heterogeneity in colorectal cancer

Colorectal cancer (CRC) is a genetically heterogeneous disease that develops and progresses through several distinct pathways characterized by genomic instability. In recent years, it has emerged that inherent phenotypic plasticity in some populations of CRC cells can contribute to heterogeneity in...

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Bibliographic Details
Main Authors: Lloyd ePereira, John eMariadason, Ross eHannan, Amardeep Singh Dhillon
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Oncology
Subjects:
Epithelial-Mesenchymal Transition
Cancer stem cell
CRC
subtypes
Tumour progression
Serrated
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00013/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00013/full

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