Computational Screening of Newly Designed Compounds against Coxsackievirus A16 and Enterovirus A71

Computational Screening of Newly Designed Compounds against Coxsackievirus A16 and Enterovirus A71

Outbreaks of hand, foot, and mouth disease (HFMD) that occur worldwide are mainly caused by the Coxsackievirus-A16 (CV-A16) and Enterovirus-A71 (EV-A71). Unfortunately, neither an anti-HFMD drug nor a vaccine is currently available. Rupintrivir in phase II clinical trial candidate for rhinovirus sho...

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Bibliographic Details
Main Authors: Amita Sripattaraphan, Kamonpan Sanachai, Warinthorn Chavasiri, Siwaporn Boonyasuppayakorn, Phornphimon Maitarad, Thanyada Rungrotmongkol
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
hand foot and mouth disease
coxsackievirus A16
enterovirus A71
3C protease
in silico drug design
Online Access:https://www.mdpi.com/1420-3049/27/6/1908

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