Serum Neurofilament Light Chain Is Associated with Incident Lacunes in Progressive Cerebral Small Vessel Disease

Serum Neurofilament Light Chain Is Associated with Incident Lacunes in Progressive Cerebral Small Vessel Disease

Background and Purpose Serum neurofilament light (NfL)-chain is a circulating marker for neuroaxonal injury and is also associated with severity of cerebral small vessel disease (SVD) cross-sectionally. Here we explored the association of serum-NfL with imaging and cognitive measures in SVD longitud...

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Bibliographic Details
Main Authors: Nils Peters, Esther van Leijsen, Anil M. Tuladhar, Christian Barro, Marek J. Konieczny, Michael Ewers, Philippe Lyrer, Stefan T. Engelter, Jens Kuhle, Marco Duering, Frank-Erik de Leeuw
Format: Article
Language:English
Published: Korean Stroke Society 2020-09-01
Series:Journal of Stroke
Subjects:
stroke
dementia
small vessel diseases
neurofilament
magnetic resonance imaging
biomarkers
Online Access:http://www.j-stroke.org/upload/pdf/jos-2019-02845.pdf

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