Mandibular small cell osteosarcoma: a case report and review of literature
Abstract Background Small cell osteosarcoma is an extremely rare histopathological variant of conventional osteosarcoma. Due to nonspecific symptoms, most osteosarcomas of the jaws are misdiagnosed as periapical abscesses and mistreated by teeth extraction and drainage. Case presentation We report,...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-09-01
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| Series: | Journal of the Egyptian National Cancer Institute |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43046-023-00191-2 |
| _version_ | 1827633409519779840 |
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| author | Hatem Wael Amer Hana’a Hezam Algadi Shyma’a Ahmed Hamza |
| author_facet | Hatem Wael Amer Hana’a Hezam Algadi Shyma’a Ahmed Hamza |
| author_sort | Hatem Wael Amer |
| collection | DOAJ |
| description | Abstract Background Small cell osteosarcoma is an extremely rare histopathological variant of conventional osteosarcoma. Due to nonspecific symptoms, most osteosarcomas of the jaws are misdiagnosed as periapical abscesses and mistreated by teeth extraction and drainage. Case presentation We report, to our knowledge, the seventh case of small cell osteosarcoma in gnathic sites affecting the mandible of an old female with history of a large painful swelling related to the right mandibular molar area for 2 months. Cone-beam computed tomography scan showed an osteolytic lesion related to the lower molar area with involvement of the inferior alveolar nerve. An incisional biopsy was taken, and after histopathological examination and immunohistochemical staining, a diagnosis of small cell osteosarcoma was reached. Hemi-mandibulectomy was performed by a maxillofacial surgeon. No clinical evidence for recurrence was noted until manuscript writing. Conclusion Accurate diagnosis is very important, and general practitioners should be aware of this entity considering that small cell osteosarcoma has a poor prognosis when compared to conventional osteosarcoma. |
| first_indexed | 2024-03-09T14:59:20Z |
| format | Article |
| id | doaj.art-b7cae9901d634ccd8fb209e2e090e1bf |
| institution | Directory Open Access Journal |
| issn | 2589-0409 |
| language | English |
| last_indexed | 2024-03-09T14:59:20Z |
| publishDate | 2023-09-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Journal of the Egyptian National Cancer Institute |
| spelling | doaj.art-b7cae9901d634ccd8fb209e2e090e1bf2023-11-26T14:00:03ZengSpringerOpenJournal of the Egyptian National Cancer Institute2589-04092023-09-013511610.1186/s43046-023-00191-2Mandibular small cell osteosarcoma: a case report and review of literatureHatem Wael Amer0Hana’a Hezam Algadi1Shyma’a Ahmed Hamza2Oral and Maxillofacial Pathology Department, Faculty of Dentistry, Cairo UniversityOral and Maxillofacial Pathology Department, Faculty of Dentistry, Cairo UniversityOral and Maxillofacial Pathology Department, Faculty of Dentistry, Cairo UniversityAbstract Background Small cell osteosarcoma is an extremely rare histopathological variant of conventional osteosarcoma. Due to nonspecific symptoms, most osteosarcomas of the jaws are misdiagnosed as periapical abscesses and mistreated by teeth extraction and drainage. Case presentation We report, to our knowledge, the seventh case of small cell osteosarcoma in gnathic sites affecting the mandible of an old female with history of a large painful swelling related to the right mandibular molar area for 2 months. Cone-beam computed tomography scan showed an osteolytic lesion related to the lower molar area with involvement of the inferior alveolar nerve. An incisional biopsy was taken, and after histopathological examination and immunohistochemical staining, a diagnosis of small cell osteosarcoma was reached. Hemi-mandibulectomy was performed by a maxillofacial surgeon. No clinical evidence for recurrence was noted until manuscript writing. Conclusion Accurate diagnosis is very important, and general practitioners should be aware of this entity considering that small cell osteosarcoma has a poor prognosis when compared to conventional osteosarcoma.https://doi.org/10.1186/s43046-023-00191-2Small cell osteosarcomaOsteosarcomaBone tumorsMandibular osteosarcomaJaws neoplasmsCase report |
| spellingShingle | Hatem Wael Amer Hana’a Hezam Algadi Shyma’a Ahmed Hamza Mandibular small cell osteosarcoma: a case report and review of literature Journal of the Egyptian National Cancer Institute Small cell osteosarcoma Osteosarcoma Bone tumors Mandibular osteosarcoma Jaws neoplasms Case report |
| title | Mandibular small cell osteosarcoma: a case report and review of literature |
| title_full | Mandibular small cell osteosarcoma: a case report and review of literature |
| title_fullStr | Mandibular small cell osteosarcoma: a case report and review of literature |
| title_full_unstemmed | Mandibular small cell osteosarcoma: a case report and review of literature |
| title_short | Mandibular small cell osteosarcoma: a case report and review of literature |
| title_sort | mandibular small cell osteosarcoma a case report and review of literature |
| topic | Small cell osteosarcoma Osteosarcoma Bone tumors Mandibular osteosarcoma Jaws neoplasms Case report |
| url | https://doi.org/10.1186/s43046-023-00191-2 |
| work_keys_str_mv | AT hatemwaelamer mandibularsmallcellosteosarcomaacasereportandreviewofliterature AT hanaahezamalgadi mandibularsmallcellosteosarcomaacasereportandreviewofliterature AT shymaaahmedhamza mandibularsmallcellosteosarcomaacasereportandreviewofliterature |