Effectiveness of confidential unit exclusion in screening blood donors of the regional blood bank in Londrina, Paraná State
BACKGROUND: For transfusion purposes, blood donors must be accepted both in clinical and serological evaluations and must not have excluded their own donation using the confidential unit exclusion. AIMS: The objective of this study was to verify whether blood donors who choose self exclusion are mor...
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| Format: | Article |
| Language: | English |
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Elsevier
2011-10-01
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| Series: | Revista Brasileira de Hematologia e Hemoterapia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842011000500010 |
| _version_ | 1818902409835970560 |
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| author | Ingridt Hildegard Vogler Mariza Saito Adriana Aparecida Spinosa Marilza Celina da Silva Egberto Munhoz Edna Maria Vissoci Reiche |
| author_facet | Ingridt Hildegard Vogler Mariza Saito Adriana Aparecida Spinosa Marilza Celina da Silva Egberto Munhoz Edna Maria Vissoci Reiche |
| author_sort | Ingridt Hildegard Vogler |
| collection | DOAJ |
| description | BACKGROUND: For transfusion purposes, blood donors must be accepted both in clinical and serological evaluations and must not have excluded their own donation using the confidential unit exclusion. AIMS: The objective of this study was to verify whether blood donors who choose self exclusion are more likely to be positive in serological tests than donors who do not. METHODS: A cross-sectional analysis was carried out of 51,861 consecutive whole blood donations from January 2004 to December 2008 at a public blood bank in Londrina, Southern Brazil. RESULTS: Self exclusion was chosen in 1672 (3.2%) donations, most frequently by first-time blood donors (p-value < 0.0001), by blood donors from external collections (p-value < 0.0001), by men (p value < 0.0001) and by under 30-year-old donors (p-value < 0.0001). The frequency of positive serology was 5.3% in the group that chose self exclusion and 3.5% in the group that did not choose self exclusion (p-value < 0.0001). CONCLUSIONS: These results show that confidential unit exclusion used in this blood bank is effective and is inexpensive. However, the diagnostic power to detect blood-borne infections was low and resulted in the discard of a high number of blood bags without any direct or indirect serologic markers of pathogens. The use of confidential unit exclusion could be replaced with molecular tests to screen blood donors. |
| first_indexed | 2024-12-19T20:35:12Z |
| format | Article |
| id | doaj.art-b7cdc9846db3470e9389656a24b567b3 |
| institution | Directory Open Access Journal |
| issn | 1516-8484 1806-0870 |
| language | English |
| last_indexed | 2024-12-19T20:35:12Z |
| publishDate | 2011-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Revista Brasileira de Hematologia e Hemoterapia |
| spelling | doaj.art-b7cdc9846db3470e9389656a24b567b32022-12-21T20:06:35ZengElsevierRevista Brasileira de Hematologia e Hemoterapia1516-84841806-08702011-10-0133534735210.5581/1516-8484.20110097Effectiveness of confidential unit exclusion in screening blood donors of the regional blood bank in Londrina, Paraná StateIngridt Hildegard VoglerMariza SaitoAdriana Aparecida SpinosaMarilza Celina da SilvaEgberto MunhozEdna Maria Vissoci ReicheBACKGROUND: For transfusion purposes, blood donors must be accepted both in clinical and serological evaluations and must not have excluded their own donation using the confidential unit exclusion. AIMS: The objective of this study was to verify whether blood donors who choose self exclusion are more likely to be positive in serological tests than donors who do not. METHODS: A cross-sectional analysis was carried out of 51,861 consecutive whole blood donations from January 2004 to December 2008 at a public blood bank in Londrina, Southern Brazil. RESULTS: Self exclusion was chosen in 1672 (3.2%) donations, most frequently by first-time blood donors (p-value < 0.0001), by blood donors from external collections (p-value < 0.0001), by men (p value < 0.0001) and by under 30-year-old donors (p-value < 0.0001). The frequency of positive serology was 5.3% in the group that chose self exclusion and 3.5% in the group that did not choose self exclusion (p-value < 0.0001). CONCLUSIONS: These results show that confidential unit exclusion used in this blood bank is effective and is inexpensive. However, the diagnostic power to detect blood-borne infections was low and resulted in the discard of a high number of blood bags without any direct or indirect serologic markers of pathogens. The use of confidential unit exclusion could be replaced with molecular tests to screen blood donors.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842011000500010Donor selectionSerologic testsDiagnosisBlood transfusion |
| spellingShingle | Ingridt Hildegard Vogler Mariza Saito Adriana Aparecida Spinosa Marilza Celina da Silva Egberto Munhoz Edna Maria Vissoci Reiche Effectiveness of confidential unit exclusion in screening blood donors of the regional blood bank in Londrina, Paraná State Revista Brasileira de Hematologia e Hemoterapia Donor selection Serologic tests Diagnosis Blood transfusion |
| title | Effectiveness of confidential unit exclusion in screening blood donors of the regional blood bank in Londrina, Paraná State |
| title_full | Effectiveness of confidential unit exclusion in screening blood donors of the regional blood bank in Londrina, Paraná State |
| title_fullStr | Effectiveness of confidential unit exclusion in screening blood donors of the regional blood bank in Londrina, Paraná State |
| title_full_unstemmed | Effectiveness of confidential unit exclusion in screening blood donors of the regional blood bank in Londrina, Paraná State |
| title_short | Effectiveness of confidential unit exclusion in screening blood donors of the regional blood bank in Londrina, Paraná State |
| title_sort | effectiveness of confidential unit exclusion in screening blood donors of the regional blood bank in londrina parana state |
| topic | Donor selection Serologic tests Diagnosis Blood transfusion |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842011000500010 |
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