Computational approach to evaluate scRNA-seq data quality and gene body coverage with SkewC

Summary: SkewC is a single-cell RNA sequencing (scRNA-seq) data quality evaluation tool. The approach is based on determining gene body coverage, and its skewness, as a quality metric for each individual cell. SkewC distinguishes between two types of single cells: typical cells with prototypical gen...

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Bibliographic Details
Main Authors: Imad Abugessaisa, Akira Hasegawa, Shintaro Katayama, Juha Kere, Takeya Kasukawa
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722009170

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