SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa
Reverse-zoonotic infections of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) from humans to wildlife species internationally raise concern over the emergence of new variants in animals. A better understanding of the transmission dynamics and pathogenesis in susceptible species...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-01-01
|
| Series: | Viruses |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4915/14/1/120 |
| _version_ | 1827662153093480448 |
|---|---|
| author | Katja Natalie Koeppel Adriano Mendes Amy Strydom Lia Rotherham Misheck Mulumba Marietjie Venter |
| author_facet | Katja Natalie Koeppel Adriano Mendes Amy Strydom Lia Rotherham Misheck Mulumba Marietjie Venter |
| author_sort | Katja Natalie Koeppel |
| collection | DOAJ |
| description | Reverse-zoonotic infections of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) from humans to wildlife species internationally raise concern over the emergence of new variants in animals. A better understanding of the transmission dynamics and pathogenesis in susceptible species will mitigate the risk to humans and wildlife occurring in Africa. Here we report infection of an exotic puma (July 2020) and three African lions (July 2021) in the same private zoo in Johannesburg, South Africa. One Health genomic surveillance identified transmission of a Delta variant from a zookeeper to the three lions, similar to those circulating in humans in South Africa. One lion developed pneumonia while the other cases had mild infection. Both the puma and lions remained positive for SARS-CoV-2 RNA for up to 7 weeks. |
| first_indexed | 2024-03-10T00:21:09Z |
| format | Article |
| id | doaj.art-b7cfab639c8a4eecaf6d2a61402f2196 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T00:21:09Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-b7cfab639c8a4eecaf6d2a61402f21962023-11-23T15:42:33ZengMDPI AGViruses1999-49152022-01-0114112010.3390/v14010120SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South AfricaKatja Natalie Koeppel0Adriano Mendes1Amy Strydom2Lia Rotherham3Misheck Mulumba4Marietjie Venter5Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, Pretoria 0110, South AfricaZoonotic Arbo- and Respiratory Virus Program, Centre for Viral Zoonoses, Department for Medical Virology, University of Pretoria, Pretoria 0110, South AfricaZoonotic Arbo- and Respiratory Virus Program, Centre for Viral Zoonoses, Department for Medical Virology, University of Pretoria, Pretoria 0110, South AfricaOnderstepoort Veterinary Research Institute, Agricultural Research Council, Onderstepoort, Pretoria 0110, South AfricaOnderstepoort Veterinary Research Institute, Agricultural Research Council, Onderstepoort, Pretoria 0110, South AfricaZoonotic Arbo- and Respiratory Virus Program, Centre for Viral Zoonoses, Department for Medical Virology, University of Pretoria, Pretoria 0110, South AfricaReverse-zoonotic infections of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) from humans to wildlife species internationally raise concern over the emergence of new variants in animals. A better understanding of the transmission dynamics and pathogenesis in susceptible species will mitigate the risk to humans and wildlife occurring in Africa. Here we report infection of an exotic puma (July 2020) and three African lions (July 2021) in the same private zoo in Johannesburg, South Africa. One Health genomic surveillance identified transmission of a Delta variant from a zookeeper to the three lions, similar to those circulating in humans in South Africa. One lion developed pneumonia while the other cases had mild infection. Both the puma and lions remained positive for SARS-CoV-2 RNA for up to 7 weeks.https://www.mdpi.com/1999-4915/14/1/120SARS-CoV-2reverse zoonosiswildlife |
| spellingShingle | Katja Natalie Koeppel Adriano Mendes Amy Strydom Lia Rotherham Misheck Mulumba Marietjie Venter SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa Viruses SARS-CoV-2 reverse zoonosis wildlife |
| title | SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa |
| title_full | SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa |
| title_fullStr | SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa |
| title_full_unstemmed | SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa |
| title_short | SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa |
| title_sort | sars cov 2 reverse zoonoses to pumas and lions south africa |
| topic | SARS-CoV-2 reverse zoonosis wildlife |
| url | https://www.mdpi.com/1999-4915/14/1/120 |
| work_keys_str_mv | AT katjanataliekoeppel sarscov2reversezoonosestopumasandlionssouthafrica AT adrianomendes sarscov2reversezoonosestopumasandlionssouthafrica AT amystrydom sarscov2reversezoonosestopumasandlionssouthafrica AT liarotherham sarscov2reversezoonosestopumasandlionssouthafrica AT misheckmulumba sarscov2reversezoonosestopumasandlionssouthafrica AT marietjieventer sarscov2reversezoonosestopumasandlionssouthafrica |