A novel field-based molecular assay to detect validated artemisinin-resistant k13 mutants

A novel field-based molecular assay to detect validated artemisinin-resistant k13 mutants

Abstract Background Given the risk of artemisinin resistance spreading from the Greater Mekong sub-region, prospective monitoring in sub-Saharan Africa should be expedited. Molecular biology techniques used for monitoring rely on the detection of k13 validated mutants by using PCR and Sanger sequenc...

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Bibliographic Details
Main Authors: Laurence Vachot-Ganée, Nimol Khim, Alexandra Iannello, Eric Legrand, Saorin Kim, Rotha Eam, Chanra Khean, Malen Ken, Elizabeth Ashley, Kyaw Myo Tun, Mehul Dhorda, François Nosten, Issa Mahamat Souleymane, Sophie Blein, Alexandre Pachot, Frédéric Ariey, Karine Kaiser, Didier Ménard
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Malaria Journal
Subjects:
Malaria
Plasmodium falciparum
Artemisinin resistance
k13 mutation detection
Surveillance
Online Access:http://link.springer.com/article/10.1186/s12936-018-2329-y

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