Application of smart devices in investigating the effects of air pollution on atrial fibrillation onset
Abstract Few studies have examined the link between short-term exposure to air pollutants and atrial fibrillation (AF) episodes. This study aims to examine the association of hourly criteria air pollutants with AF episodes. We employ a smart device-based photoplethysmography technology to screen AF...
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| Format: | Article |
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Nature Portfolio
2023-03-01
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| Series: | npj Digital Medicine |
| Online Access: | https://doi.org/10.1038/s41746-023-00788-w |
| _version_ | 1797420714147446784 |
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| author | Cong Liu Meihui Tai Jialu Hu Xinlei Zhu Weidong Wang Yutao Guo Haidong Kan Renjie Chen |
| author_facet | Cong Liu Meihui Tai Jialu Hu Xinlei Zhu Weidong Wang Yutao Guo Haidong Kan Renjie Chen |
| author_sort | Cong Liu |
| collection | DOAJ |
| description | Abstract Few studies have examined the link between short-term exposure to air pollutants and atrial fibrillation (AF) episodes. This study aims to examine the association of hourly criteria air pollutants with AF episodes. We employ a smart device-based photoplethysmography technology to screen AF from 2018 to 2021. Hourly concentrations of six criteria air pollutants are matched to the onset hour of AF for each participant. We adopt a time-stratified case-crossover design to capture the acute effects of air pollutants on AF episodes, using conditional logistic regression models. Subgroup analyses are conducted by age, gender, and season. A total of 11,906 episodes of AF are identified in 2976 participants from 288 Chinese cities. Generally, the strongest associations of air pollutants are present at lag 18–24 h, with positive and linear exposure-response relationships. For an interquartile range increase in inhalable particles, fine particles, nitrogen dioxide, and carbon monoxide, the odds ratio (OR) of AF is 1.19 [95% confidential interval (CI): 1.03, 1.37], 1.38 (95%CI: 1.14, 1.67), 1.60 (95%CI: 1.16, 2.20) and 1.48 (95%CI: 1.19, 1.84), respectively. The estimates are robust to the adjustment of co-pollutants, and they are larger in females, older people, and in cold seasons. There are insignificant associations for sulfur dioxide and ozone. This nationwide case-crossover study demonstrates robust evidence of significant associations between hourly exposure to air pollutants and the onset of AF episodes, which underscores the importance of ongoing efforts to further improve air quality as an effective target for AF prevention. |
| first_indexed | 2024-03-09T07:06:34Z |
| format | Article |
| id | doaj.art-b7e0ac94e4b4444889d0b5381b4d6064 |
| institution | Directory Open Access Journal |
| issn | 2398-6352 |
| language | English |
| last_indexed | 2024-03-09T07:06:34Z |
| publishDate | 2023-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Digital Medicine |
| spelling | doaj.art-b7e0ac94e4b4444889d0b5381b4d60642023-12-03T09:32:20ZengNature Portfolionpj Digital Medicine2398-63522023-03-01611810.1038/s41746-023-00788-wApplication of smart devices in investigating the effects of air pollution on atrial fibrillation onsetCong Liu0Meihui Tai1Jialu Hu2Xinlei Zhu3Weidong Wang4Yutao Guo5Haidong Kan6Renjie Chen7School of Public Health, Shanghai Institute of Infectious Disease and Biosecurity, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan UniversityPulmonary Vessel and Thrombotic Disease, Sixth Medical Center, Chinese PLA General HospitalDepartment of Cardiology, Zhongshan Hospital Affiliated to Fudan UniversitySchool of Public Health, Shanghai Institute of Infectious Disease and Biosecurity, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan UniversitySchool of Public Health, Shanghai Institute of Infectious Disease and Biosecurity, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan UniversityPulmonary Vessel and Thrombotic Disease, Sixth Medical Center, Chinese PLA General HospitalSchool of Public Health, Shanghai Institute of Infectious Disease and Biosecurity, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan UniversitySchool of Public Health, Shanghai Institute of Infectious Disease and Biosecurity, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan UniversityAbstract Few studies have examined the link between short-term exposure to air pollutants and atrial fibrillation (AF) episodes. This study aims to examine the association of hourly criteria air pollutants with AF episodes. We employ a smart device-based photoplethysmography technology to screen AF from 2018 to 2021. Hourly concentrations of six criteria air pollutants are matched to the onset hour of AF for each participant. We adopt a time-stratified case-crossover design to capture the acute effects of air pollutants on AF episodes, using conditional logistic regression models. Subgroup analyses are conducted by age, gender, and season. A total of 11,906 episodes of AF are identified in 2976 participants from 288 Chinese cities. Generally, the strongest associations of air pollutants are present at lag 18–24 h, with positive and linear exposure-response relationships. For an interquartile range increase in inhalable particles, fine particles, nitrogen dioxide, and carbon monoxide, the odds ratio (OR) of AF is 1.19 [95% confidential interval (CI): 1.03, 1.37], 1.38 (95%CI: 1.14, 1.67), 1.60 (95%CI: 1.16, 2.20) and 1.48 (95%CI: 1.19, 1.84), respectively. The estimates are robust to the adjustment of co-pollutants, and they are larger in females, older people, and in cold seasons. There are insignificant associations for sulfur dioxide and ozone. This nationwide case-crossover study demonstrates robust evidence of significant associations between hourly exposure to air pollutants and the onset of AF episodes, which underscores the importance of ongoing efforts to further improve air quality as an effective target for AF prevention.https://doi.org/10.1038/s41746-023-00788-w |
| spellingShingle | Cong Liu Meihui Tai Jialu Hu Xinlei Zhu Weidong Wang Yutao Guo Haidong Kan Renjie Chen Application of smart devices in investigating the effects of air pollution on atrial fibrillation onset npj Digital Medicine |
| title | Application of smart devices in investigating the effects of air pollution on atrial fibrillation onset |
| title_full | Application of smart devices in investigating the effects of air pollution on atrial fibrillation onset |
| title_fullStr | Application of smart devices in investigating the effects of air pollution on atrial fibrillation onset |
| title_full_unstemmed | Application of smart devices in investigating the effects of air pollution on atrial fibrillation onset |
| title_short | Application of smart devices in investigating the effects of air pollution on atrial fibrillation onset |
| title_sort | application of smart devices in investigating the effects of air pollution on atrial fibrillation onset |
| url | https://doi.org/10.1038/s41746-023-00788-w |
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