The Inverted-U Relationship Between Dietary Inflammatory Potential and Hearing Loss Among Adults Aged 20 Years and Over in the United States: A Cross-Sectional Study
Yanpeng Fu,1 Wenyu Chen,2 Liqing Guo,1 Yuehui Liu1 1Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of China; 2Nursing Department, Second Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2021-12-01
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| Series: | Journal of Inflammation Research |
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| Online Access: | https://www.dovepress.com/the-inverted-u-relationship-between-dietary-inflammatory-potential-and-peer-reviewed-fulltext-article-JIR |
| _version_ | 1818388596724334592 |
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| author | Fu Y Chen W Guo L Liu Y |
| author_facet | Fu Y Chen W Guo L Liu Y |
| author_sort | Fu Y |
| collection | DOAJ |
| description | Yanpeng Fu,1 Wenyu Chen,2 Liqing Guo,1 Yuehui Liu1 1Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of China; 2Nursing Department, Second Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of ChinaCorrespondence: Yuehui LiuDepartment of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, People’s Republic of ChinaEmail liuyuehuiclark@21cn.comPurpose: The purpose of this study was to examine the relationship between dietary inflammatory index and objective hearing loss (HL).Materials and Methods: A cross‐sectional analysis of a nationally representative sample of participants was performed based on data in National Health and Nutrition Examination Survey (NHANES) (2009– 2016). HL was defined as pure tone averages > 25 dB at 500, 1000, and 2000 Hz (low frequency); 3000, 4000, 6000, and 8000 Hz (high frequency) in either ear. The energy‐adjusted dietary inflammatory index (E‐DII) score was calculated for each participant based on two 24‐h dietary recalls to assess diet‐associated inflammation. Multivariable logistic regression was used to examine the linear relationship between HL and E‐DII score or E-DII quartiles. Restricted cubic spline was applied to identify any non‐linear associations of the E‐DII score with hearing loss. Subgroup analyses were performed by age and gender to explore the moderating roles of these factors. Akaike’s Information Criterion (AIC) values were used to select the better-fitted model among linear and non-linear models.Results: An inverted-U shaped relationship with low-frequency hearing loss (LFHL) was identified for the E‐DII score (P-nonlinear =0.023) after adjustment for potential confounders. But significant linear or nonlinear association between E-DII score and high-frequency hearing loss (HFHL) was not found.Conclusion: E-DII score had inverted-U relationship with LFHL. Both pro-inflammatory diet and anti-inflammatory diet seemed to be associated with a decreased risk of LFHL compared to diet that was neither pro-inflammatory diet nor anti-inflammatory diet.Keywords: dietary inflammatory index, inflammation, NHANES, hearing loss |
| first_indexed | 2024-12-14T04:28:21Z |
| format | Article |
| id | doaj.art-b7e62853de9f40938c05da3be3a705ba |
| institution | Directory Open Access Journal |
| issn | 1178-7031 |
| language | English |
| last_indexed | 2024-12-14T04:28:21Z |
| publishDate | 2021-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Journal of Inflammation Research |
| spelling | doaj.art-b7e62853de9f40938c05da3be3a705ba2022-12-21T23:17:09ZengDove Medical PressJournal of Inflammation Research1178-70312021-12-01Volume 146671668371304The Inverted-U Relationship Between Dietary Inflammatory Potential and Hearing Loss Among Adults Aged 20 Years and Over in the United States: A Cross-Sectional StudyFu YChen WGuo LLiu YYanpeng Fu,1 Wenyu Chen,2 Liqing Guo,1 Yuehui Liu1 1Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of China; 2Nursing Department, Second Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of ChinaCorrespondence: Yuehui LiuDepartment of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, People’s Republic of ChinaEmail liuyuehuiclark@21cn.comPurpose: The purpose of this study was to examine the relationship between dietary inflammatory index and objective hearing loss (HL).Materials and Methods: A cross‐sectional analysis of a nationally representative sample of participants was performed based on data in National Health and Nutrition Examination Survey (NHANES) (2009– 2016). HL was defined as pure tone averages > 25 dB at 500, 1000, and 2000 Hz (low frequency); 3000, 4000, 6000, and 8000 Hz (high frequency) in either ear. The energy‐adjusted dietary inflammatory index (E‐DII) score was calculated for each participant based on two 24‐h dietary recalls to assess diet‐associated inflammation. Multivariable logistic regression was used to examine the linear relationship between HL and E‐DII score or E-DII quartiles. Restricted cubic spline was applied to identify any non‐linear associations of the E‐DII score with hearing loss. Subgroup analyses were performed by age and gender to explore the moderating roles of these factors. Akaike’s Information Criterion (AIC) values were used to select the better-fitted model among linear and non-linear models.Results: An inverted-U shaped relationship with low-frequency hearing loss (LFHL) was identified for the E‐DII score (P-nonlinear =0.023) after adjustment for potential confounders. But significant linear or nonlinear association between E-DII score and high-frequency hearing loss (HFHL) was not found.Conclusion: E-DII score had inverted-U relationship with LFHL. Both pro-inflammatory diet and anti-inflammatory diet seemed to be associated with a decreased risk of LFHL compared to diet that was neither pro-inflammatory diet nor anti-inflammatory diet.Keywords: dietary inflammatory index, inflammation, NHANES, hearing losshttps://www.dovepress.com/the-inverted-u-relationship-between-dietary-inflammatory-potential-and-peer-reviewed-fulltext-article-JIRdietary inflammatory indexinflammationnhaneshearing loss. |
| spellingShingle | Fu Y Chen W Guo L Liu Y The Inverted-U Relationship Between Dietary Inflammatory Potential and Hearing Loss Among Adults Aged 20 Years and Over in the United States: A Cross-Sectional Study Journal of Inflammation Research dietary inflammatory index inflammation nhanes hearing loss. |
| title | The Inverted-U Relationship Between Dietary Inflammatory Potential and Hearing Loss Among Adults Aged 20 Years and Over in the United States: A Cross-Sectional Study |
| title_full | The Inverted-U Relationship Between Dietary Inflammatory Potential and Hearing Loss Among Adults Aged 20 Years and Over in the United States: A Cross-Sectional Study |
| title_fullStr | The Inverted-U Relationship Between Dietary Inflammatory Potential and Hearing Loss Among Adults Aged 20 Years and Over in the United States: A Cross-Sectional Study |
| title_full_unstemmed | The Inverted-U Relationship Between Dietary Inflammatory Potential and Hearing Loss Among Adults Aged 20 Years and Over in the United States: A Cross-Sectional Study |
| title_short | The Inverted-U Relationship Between Dietary Inflammatory Potential and Hearing Loss Among Adults Aged 20 Years and Over in the United States: A Cross-Sectional Study |
| title_sort | inverted u relationship between dietary inflammatory potential and hearing loss among adults aged 20 years and over in the united states a cross sectional study |
| topic | dietary inflammatory index inflammation nhanes hearing loss. |
| url | https://www.dovepress.com/the-inverted-u-relationship-between-dietary-inflammatory-potential-and-peer-reviewed-fulltext-article-JIR |
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