Long-term Clinical Outcomes of Coronary Rotational Atherectomy for Specific Indications
Objective: This study compared the long-term outcomes between rotational atherectomy (RA) for specific indications and on-label use of RA for severely calcified coronary lesions. Methods: Data for patients who underwent RA between 2015 and 2020 in a single-center registry were analyzed. The specif...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Compuscript Ltd
2023-04-01
|
| Series: | Cardiovascular Innovations and Applications |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0016 |
| _version_ | 1797454514457935872 |
|---|---|
| author | Cheng-fu Cao Wei-li Teng Yu-liang Ma Qi Li Hong Zhao Ming-yu Lu Jian Liu Wei-min Wang |
| author_facet | Cheng-fu Cao Wei-li Teng Yu-liang Ma Qi Li Hong Zhao Ming-yu Lu Jian Liu Wei-min Wang |
| author_sort | Cheng-fu Cao |
| collection | DOAJ |
| description | Objective: This study compared the long-term outcomes between rotational atherectomy (RA) for specific indications and on-label use of RA for severely calcified coronary lesions. Methods: Data for patients who underwent RA between 2015 and 2020 in a single-center registry were analyzed. The specific indication group included patients with ostial lesions, unprotected left main coronary artery stenosis, chronic total occlusions, stent ablation, angulated lesions, and cardiac dysfunction, whereas patients with none of the above-mentioned characteristics were included in the on-label group. The primary endpoint was compared between groups. Results: A total of 176 patients in the on-label group and 125 patients in the specific indication group were included. Patient clinical characteristics were comparable between groups. The incidence of complications during the procedure was higher in the specific indication group than in the on-label group (20.0% vs. 10.8%, P=0.018). No significant difference was observed in in-hospital MACCE between groups (12.5% vs 9.7%, P=0.392). During 35 (10–57) months of follow-up, MACCE occurred in 46 patients (15.3%). The incidence of MACCE was much higher in the specific indication group than the on-label group (25.6% vs 13.6%, P=0.034). Conclusions: RA for specific indications, compared with on-label use, had a higher incidence of complications during the procedure and poorer long-term clinical outcomes. |
| first_indexed | 2024-03-09T15:38:19Z |
| format | Article |
| id | doaj.art-b7e7f6b33f3a4f94860269fc209a5944 |
| institution | Directory Open Access Journal |
| issn | 2009-8618 2009-8782 |
| language | English |
| last_indexed | 2024-03-09T15:38:19Z |
| publishDate | 2023-04-01 |
| publisher | Compuscript Ltd |
| record_format | Article |
| series | Cardiovascular Innovations and Applications |
| spelling | doaj.art-b7e7f6b33f3a4f94860269fc209a59442023-11-25T17:00:39ZengCompuscript LtdCardiovascular Innovations and Applications2009-86182009-87822023-04-018198410.15212/CVIA.2023.0016Long-term Clinical Outcomes of Coronary Rotational Atherectomy for Specific IndicationsCheng-fu CaoWei-li TengYu-liang MaQi LiHong ZhaoMing-yu LuJian LiuWei-min WangObjective: This study compared the long-term outcomes between rotational atherectomy (RA) for specific indications and on-label use of RA for severely calcified coronary lesions. Methods: Data for patients who underwent RA between 2015 and 2020 in a single-center registry were analyzed. The specific indication group included patients with ostial lesions, unprotected left main coronary artery stenosis, chronic total occlusions, stent ablation, angulated lesions, and cardiac dysfunction, whereas patients with none of the above-mentioned characteristics were included in the on-label group. The primary endpoint was compared between groups. Results: A total of 176 patients in the on-label group and 125 patients in the specific indication group were included. Patient clinical characteristics were comparable between groups. The incidence of complications during the procedure was higher in the specific indication group than in the on-label group (20.0% vs. 10.8%, P=0.018). No significant difference was observed in in-hospital MACCE between groups (12.5% vs 9.7%, P=0.392). During 35 (10–57) months of follow-up, MACCE occurred in 46 patients (15.3%). The incidence of MACCE was much higher in the specific indication group than the on-label group (25.6% vs 13.6%, P=0.034). Conclusions: RA for specific indications, compared with on-label use, had a higher incidence of complications during the procedure and poorer long-term clinical outcomes.https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0016 |
| spellingShingle | Cheng-fu Cao Wei-li Teng Yu-liang Ma Qi Li Hong Zhao Ming-yu Lu Jian Liu Wei-min Wang Long-term Clinical Outcomes of Coronary Rotational Atherectomy for Specific Indications Cardiovascular Innovations and Applications |
| title | Long-term Clinical Outcomes of Coronary Rotational Atherectomy for Specific Indications |
| title_full | Long-term Clinical Outcomes of Coronary Rotational Atherectomy for Specific Indications |
| title_fullStr | Long-term Clinical Outcomes of Coronary Rotational Atherectomy for Specific Indications |
| title_full_unstemmed | Long-term Clinical Outcomes of Coronary Rotational Atherectomy for Specific Indications |
| title_short | Long-term Clinical Outcomes of Coronary Rotational Atherectomy for Specific Indications |
| title_sort | long term clinical outcomes of coronary rotational atherectomy for specific indications |
| url | https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0016 |
| work_keys_str_mv | AT chengfucao longtermclinicaloutcomesofcoronaryrotationalatherectomyforspecificindications AT weiliteng longtermclinicaloutcomesofcoronaryrotationalatherectomyforspecificindications AT yuliangma longtermclinicaloutcomesofcoronaryrotationalatherectomyforspecificindications AT qili longtermclinicaloutcomesofcoronaryrotationalatherectomyforspecificindications AT hongzhao longtermclinicaloutcomesofcoronaryrotationalatherectomyforspecificindications AT mingyulu longtermclinicaloutcomesofcoronaryrotationalatherectomyforspecificindications AT jianliu longtermclinicaloutcomesofcoronaryrotationalatherectomyforspecificindications AT weiminwang longtermclinicaloutcomesofcoronaryrotationalatherectomyforspecificindications |