Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies

Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies

Renata Curciarello,1,2 Toni Sobande,2 Samantha Jones,2 Paolo Giuffrida,2,3 Antonio Di Sabatino,3 Guillermo H Docena,1 Thomas T MacDonald,2 Klaartje Kok2,4 1Instituto de Estudios Inmunológicos y Fisiopatológicos IIFP-CONICET, Universidad Nacional de La Plata, La Plata, Buenos Ai...

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Bibliographic Details
Main Authors: Curciarello R, Sobande T, Jones S, Giuffrida P, Di Sabatino A, Docena GH, MacDonald TT, Kok K
Format: Article
Language:English
Published: Dove Medical Press 2020-05-01
Series:Journal of Inflammation Research
Subjects:
elastinolytic activity
elafin
anti-tnf
inflammatory bowel disease
biological drugs.
Online Access:https://www.dovepress.com/human-neutrophil-elastase-proteolytic-activity-in-ulcerative-colitis-f-peer-reviewed-article-JIR

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