Subcellular Localization of Sprouty2 in Human Glioma Cells

Subcellular Localization of Sprouty2 in Human Glioma Cells

Sprouty proteins act ubiquitously as signaling integrators and inhibitors of receptor tyrosine kinase (RTK) activated pathways. Among the four Sprouty isoforms, Sprouty2 is a key regulator of growth factor signaling in several neurological disorders. High protein levels correlate with reduced surviv...

Full description

Bibliographic Details
Main Authors: Barbara Hausott, Jong-Whi Park, Taras Valovka, Martin Offterdinger, Michael W. Hess, Stephan Geley, Lars Klimaschewski
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
endosome
cytoskeleton
vimentin
ERK
super-resolution
electron microscopy
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00073/full

Similar Items

Similar Items