Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia
This study includes two parts, and the first was the preparation of the Zn(II)complex by reacting N-[4-(5-{(Z)-[(5-oxo-2-sulfanyl-4,5-dihydro-1H-imidazol-1-yl)imino]methyl}furan-2-yl)phenyl]acetamide with ZnCl2. The complex was characterized by using microscopic analysis such as UV-Vis spectrum, LC-...
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Format: | Article |
Language: | English |
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Department of Chemistry, Universitas Gadjah Mada
2023-08-01
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Series: | Indonesian Journal of Chemistry |
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Online Access: | https://jurnal.ugm.ac.id/ijc/article/view/82208 |
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author | Areej Ali Jarullah Nidhal Meteab Khamees Taghreed Mohy Al-Deen Musa |
author_facet | Areej Ali Jarullah Nidhal Meteab Khamees Taghreed Mohy Al-Deen Musa |
author_sort | Areej Ali Jarullah |
collection | DOAJ |
description | This study includes two parts, and the first was the preparation of the Zn(II)complex by reacting N-[4-(5-{(Z)-[(5-oxo-2-sulfanyl-4,5-dihydro-1H-imidazol-1-yl)imino]methyl}furan-2-yl)phenyl]acetamide with ZnCl2. The complex was characterized by using microscopic analysis such as UV-Vis spectrum, LC-MS, FTIR spectrophotometer, measurements of conductivity, magnetic susceptibility, and atomic absorption. The second part was the preparation of the ZnO nanoparticles by dissolving the Zn(II) complex in HNO3 and HCl and its use as a drug transporter to treat leukemia. FSEM, TEM, and XRD were examined for the characterization of ZnO nanoparticles that will be used in the synthesis of most medicines and drugs in the future. |
first_indexed | 2024-03-12T14:44:17Z |
format | Article |
id | doaj.art-b7ee2108479b4e80a11a9ae76560de2e |
institution | Directory Open Access Journal |
issn | 1411-9420 2460-1578 |
language | English |
last_indexed | 2024-03-12T14:44:17Z |
publishDate | 2023-08-01 |
publisher | Department of Chemistry, Universitas Gadjah Mada |
record_format | Article |
series | Indonesian Journal of Chemistry |
spelling | doaj.art-b7ee2108479b4e80a11a9ae76560de2e2023-08-16T03:28:31ZengDepartment of Chemistry, Universitas Gadjah MadaIndonesian Journal of Chemistry1411-94202460-15782023-08-012341071107610.22146/ijc.8220834225Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat LeukemiaAreej Ali Jarullah0Nidhal Meteab Khamees1Taghreed Mohy Al-Deen Musa2Department of Chemistry, College of Science, University of Diyala, Baquba, Diyala, IraqDepartment of Chemistry, College of Science, University of Diyala, Baquba, Diyala, IraqDepartment of Chemistry, College of Science, Mustansiriyah University, Baghdad 10052, IraqThis study includes two parts, and the first was the preparation of the Zn(II)complex by reacting N-[4-(5-{(Z)-[(5-oxo-2-sulfanyl-4,5-dihydro-1H-imidazol-1-yl)imino]methyl}furan-2-yl)phenyl]acetamide with ZnCl2. The complex was characterized by using microscopic analysis such as UV-Vis spectrum, LC-MS, FTIR spectrophotometer, measurements of conductivity, magnetic susceptibility, and atomic absorption. The second part was the preparation of the ZnO nanoparticles by dissolving the Zn(II) complex in HNO3 and HCl and its use as a drug transporter to treat leukemia. FSEM, TEM, and XRD were examined for the characterization of ZnO nanoparticles that will be used in the synthesis of most medicines and drugs in the future.https://jurnal.ugm.ac.id/ijc/article/view/82208zinc(ii)complexzno nanoparticlescarrier for anti-cancer drugsleukemiamicroscopic analysis |
spellingShingle | Areej Ali Jarullah Nidhal Meteab Khamees Taghreed Mohy Al-Deen Musa Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia Indonesian Journal of Chemistry zinc(ii)complex zno nanoparticles carrier for anti-cancer drugs leukemia microscopic analysis |
title | Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia |
title_full | Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia |
title_fullStr | Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia |
title_full_unstemmed | Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia |
title_short | Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia |
title_sort | synthesis of zno nanoparticle and utilized as a drug carrier to treat leukemia |
topic | zinc(ii)complex zno nanoparticles carrier for anti-cancer drugs leukemia microscopic analysis |
url | https://jurnal.ugm.ac.id/ijc/article/view/82208 |
work_keys_str_mv | AT areejalijarullah synthesisofznonanoparticleandutilizedasadrugcarriertotreatleukemia AT nidhalmeteabkhamees synthesisofznonanoparticleandutilizedasadrugcarriertotreatleukemia AT taghreedmohyaldeenmusa synthesisofznonanoparticleandutilizedasadrugcarriertotreatleukemia |