Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia

This study includes two parts, and the first was the preparation of the Zn(II)complex by reacting N-[4-(5-{(Z)-[(5-oxo-2-sulfanyl-4,5-dihydro-1H-imidazol-1-yl)imino]methyl}furan-2-yl)phenyl]acetamide with ZnCl2. The complex was characterized by using microscopic analysis such as UV-Vis spectrum, LC-...

Full description

Bibliographic Details
Main Authors: Areej Ali Jarullah, Nidhal Meteab Khamees, Taghreed Mohy Al-Deen Musa
Format: Article
Language:English
Published: Department of Chemistry, Universitas Gadjah Mada 2023-08-01
Series:Indonesian Journal of Chemistry
Subjects:
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/82208
_version_ 1797742626294726656
author Areej Ali Jarullah
Nidhal Meteab Khamees
Taghreed Mohy Al-Deen Musa
author_facet Areej Ali Jarullah
Nidhal Meteab Khamees
Taghreed Mohy Al-Deen Musa
author_sort Areej Ali Jarullah
collection DOAJ
description This study includes two parts, and the first was the preparation of the Zn(II)complex by reacting N-[4-(5-{(Z)-[(5-oxo-2-sulfanyl-4,5-dihydro-1H-imidazol-1-yl)imino]methyl}furan-2-yl)phenyl]acetamide with ZnCl2. The complex was characterized by using microscopic analysis such as UV-Vis spectrum, LC-MS, FTIR spectrophotometer, measurements of conductivity, magnetic susceptibility, and atomic absorption. The second part was the preparation of the ZnO nanoparticles by dissolving the Zn(II) complex in HNO3 and HCl and its use as a drug transporter to treat leukemia. FSEM, TEM, and XRD were examined for the characterization of ZnO nanoparticles that will be used in the synthesis of most medicines and drugs in the future.
first_indexed 2024-03-12T14:44:17Z
format Article
id doaj.art-b7ee2108479b4e80a11a9ae76560de2e
institution Directory Open Access Journal
issn 1411-9420
2460-1578
language English
last_indexed 2024-03-12T14:44:17Z
publishDate 2023-08-01
publisher Department of Chemistry, Universitas Gadjah Mada
record_format Article
series Indonesian Journal of Chemistry
spelling doaj.art-b7ee2108479b4e80a11a9ae76560de2e2023-08-16T03:28:31ZengDepartment of Chemistry, Universitas Gadjah MadaIndonesian Journal of Chemistry1411-94202460-15782023-08-012341071107610.22146/ijc.8220834225Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat LeukemiaAreej Ali Jarullah0Nidhal Meteab Khamees1Taghreed Mohy Al-Deen Musa2Department of Chemistry, College of Science, University of Diyala, Baquba, Diyala, IraqDepartment of Chemistry, College of Science, University of Diyala, Baquba, Diyala, IraqDepartment of Chemistry, College of Science, Mustansiriyah University, Baghdad 10052, IraqThis study includes two parts, and the first was the preparation of the Zn(II)complex by reacting N-[4-(5-{(Z)-[(5-oxo-2-sulfanyl-4,5-dihydro-1H-imidazol-1-yl)imino]methyl}furan-2-yl)phenyl]acetamide with ZnCl2. The complex was characterized by using microscopic analysis such as UV-Vis spectrum, LC-MS, FTIR spectrophotometer, measurements of conductivity, magnetic susceptibility, and atomic absorption. The second part was the preparation of the ZnO nanoparticles by dissolving the Zn(II) complex in HNO3 and HCl and its use as a drug transporter to treat leukemia. FSEM, TEM, and XRD were examined for the characterization of ZnO nanoparticles that will be used in the synthesis of most medicines and drugs in the future.https://jurnal.ugm.ac.id/ijc/article/view/82208zinc(ii)complexzno nanoparticlescarrier for anti-cancer drugsleukemiamicroscopic analysis
spellingShingle Areej Ali Jarullah
Nidhal Meteab Khamees
Taghreed Mohy Al-Deen Musa
Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia
Indonesian Journal of Chemistry
zinc(ii)complex
zno nanoparticles
carrier for anti-cancer drugs
leukemia
microscopic analysis
title Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia
title_full Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia
title_fullStr Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia
title_full_unstemmed Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia
title_short Synthesis of ZnO Nanoparticle and Utilized as a Drug Carrier to Treat Leukemia
title_sort synthesis of zno nanoparticle and utilized as a drug carrier to treat leukemia
topic zinc(ii)complex
zno nanoparticles
carrier for anti-cancer drugs
leukemia
microscopic analysis
url https://jurnal.ugm.ac.id/ijc/article/view/82208
work_keys_str_mv AT areejalijarullah synthesisofznonanoparticleandutilizedasadrugcarriertotreatleukemia
AT nidhalmeteabkhamees synthesisofznonanoparticleandutilizedasadrugcarriertotreatleukemia
AT taghreedmohyaldeenmusa synthesisofznonanoparticleandutilizedasadrugcarriertotreatleukemia