CRH-R2 signalling modulates feeding and circadian gene expression in hypothalamic mHypoA-2/30 neurons

CRH-R2 signalling modulates feeding and circadian gene expression in hypothalamic mHypoA-2/30 neurons

The hypothalamic type 2 corticotropin releasing hormone receptor (CRH-R2) plays critical roles in homeostatic regulation, particularly in fine tuning stress recovery. During acute stress, the CRH-R2 ligands CRH and urocortins promote adaptive responses and feeding inhibition. However, in rodent mode...

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Bibliographic Details
Main Authors: Viridiana Alcántara-Alonso, Robert Dallmann, Hendrik Lehnert, Patricia de Gortari, Dimitris K. Grammatopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Endocrinology
Subjects:
Feeding
hypothalamic peptides
CRH-R2
urocortin 2 (UCN2)
AMPK
CREB
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1266081/full

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