AMPK Activation Is Important for the Preservation of Insulin Sensitivity in Visceral, but Not in Subcutaneous Adipose Tissue of Postnatally Overfed Rat Model of Polycystic Ovary Syndrome

AMPK Activation Is Important for the Preservation of Insulin Sensitivity in Visceral, but Not in Subcutaneous Adipose Tissue of Postnatally Overfed Rat Model of Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is a well-known reproductive syndrome usually associated with obesity, insulin resistance, and hyperinsulinemia. Although the first signs of PCOS begin early in adolescence, it is underexplored whether peripubertal obesity predisposes women to PCOS metabolic disturba...

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Bibliographic Details
Main Authors: Bojana Mićić, Ana Teofilović, Ana Djordjevic, Nataša Veličković, Djuro Macut, Danijela Vojnović Milutinović
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
polycystic ovary syndrome
obesity
visceral adipose tissue
subcutaneous adipose tissue
insulin resistance
5α-dihydrotestosterone
Online Access:https://www.mdpi.com/1422-0067/23/16/8942

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