Cholesterol Protects Against Acute Stress-Induced T-Tubule Remodeling in Mouse Ventricular Myocytes

Cholesterol Protects Against Acute Stress-Induced T-Tubule Remodeling in Mouse Ventricular Myocytes

Efficient excitation-contraction coupling in ventricular myocytes depends critically on the presence of the t-tubular network. It has been recently demonstrated that cholesterol, a major component of the lipid bilayer, plays an important role in long-term maintenance of the integrity of t-tubular sy...

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Bibliographic Details
Main Authors: Azadeh Nikouee, Keita Uchida, Ian Moench, Anatoli N. Lopatin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Physiology
Subjects:
mouse ventricular myocytes
t-tubule
cholesterol
osmotic stress
potassium currents
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01516/full

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