Endothelial progenitor cells stimulate neonatal lung angiogenesis through FOXF1-mediated activation of BMP9/ACVRL1 signaling
The molecular mechanisms through which pulmonary endothelial progenitor cells stimulate lung angiogenesis are not clear. Here, authors show that these cells stimulate the growth of alveolar capillaries and alveoli of newborn mice through FOXF1 and FLI1 nuclear protein-activation of the BMP9/ACVRL1/S...
Main Authors: | Guolun Wang, Bingqiang Wen, Zicheng Deng, Yufang Zhang, Olena A. Kolesnichenko, Vladimir Ustiyan, Arun Pradhan, Tanya V. Kalin, Vladimir V. Kalinichenko |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-04-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-29746-y |
Similar Items
-
Hypoxia represses FOXF1 in lung endothelial cells through HIF-1α
by: Anusha Acharya, et al.
Published: (2024-01-01) -
Endothelial progenitor cells derived from embryonic stem cells prevent alveolar simplification in a murine model of bronchopulmonary dysplasia
by: Olena A. Kolesnichenko, et al.
Published: (2023-06-01) -
The bone marrow of mouse-rat chimeras contains progenitors of multiple pulmonary cell lineages
by: Enhong Li, et al.
Published: (2024-04-01) -
FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts
by: Markaisa Black, et al.
Published: (2018-04-01) -
Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression
by: Avinash V. Dharmadhikari, et al.
Published: (2016-11-01)