Use of Stromal Intervention and Exogenous Neoantigen Vaccination to Boost Pancreatic Cancer Chemo-Immunotherapy by Nanocarriers

Use of Stromal Intervention and Exogenous Neoantigen Vaccination to Boost Pancreatic Cancer Chemo-Immunotherapy by Nanocarriers

Despite the formidable treatment challenges of pancreatic ductal adenocarcinoma (PDAC), considerable progress has been made in improving drug delivery via pioneering nanocarriers. These innovations are geared towards overcoming the obstacles presented by dysplastic stroma and fostering anti-PDAC imm...

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Bibliographic Details
Main Authors: Saborni Chattopadhyay, Yu-Pei Liao, Xiang Wang, André E. Nel
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Bioengineering
Subjects:
pancreatic cancer
tumor stroma
irinotecan
lipoxins
KRAS vaccination
tertiary lymphoid structures
Online Access:https://www.mdpi.com/2306-5354/10/10/1205

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