Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole Sulfonamides

Several new substituted sulfonamide compounds were synthesized and their structures were confirmed by 1H-NMR, 13C-NMR, FT-IR, and mass spectroscopy. The antibacterial activities of the synthesized compounds were screened against standard strains of six Gram positive and four Gram negative bacteria u...

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Bibliographic Details
Main Authors: Aidil Abdul Hamid, Ekhlass M. Taha, Zanariah Abdullah, Raied M. Shakir, Yatimah Alias, Nassir N. Al-Mohammed
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/10/11978
Description
Summary:Several new substituted sulfonamide compounds were synthesized and their structures were confirmed by 1H-NMR, 13C-NMR, FT-IR, and mass spectroscopy. The antibacterial activities of the synthesized compounds were screened against standard strains of six Gram positive and four Gram negative bacteria using the microbroth dilution assay. Most of the compounds studied showed promising activities against both types of bacteria.
ISSN:1420-3049