Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole Sulfonamides
Several new substituted sulfonamide compounds were synthesized and their structures were confirmed by 1H-NMR, 13C-NMR, FT-IR, and mass spectroscopy. The antibacterial activities of the synthesized compounds were screened against standard strains of six Gram positive and four Gram negative bacteria u...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-09-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/18/10/11978 |
| _version_ | 1818526950203850752 |
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| author | Aidil Abdul Hamid Ekhlass M. Taha Zanariah Abdullah Raied M. Shakir Yatimah Alias Nassir N. Al-Mohammed |
| author_facet | Aidil Abdul Hamid Ekhlass M. Taha Zanariah Abdullah Raied M. Shakir Yatimah Alias Nassir N. Al-Mohammed |
| author_sort | Aidil Abdul Hamid |
| collection | DOAJ |
| description | Several new substituted sulfonamide compounds were synthesized and their structures were confirmed by 1H-NMR, 13C-NMR, FT-IR, and mass spectroscopy. The antibacterial activities of the synthesized compounds were screened against standard strains of six Gram positive and four Gram negative bacteria using the microbroth dilution assay. Most of the compounds studied showed promising activities against both types of bacteria. |
| first_indexed | 2024-12-11T06:29:50Z |
| format | Article |
| id | doaj.art-b7fb2d1a99be4b488479fec111445e96 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-11T06:29:50Z |
| publishDate | 2013-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-b7fb2d1a99be4b488479fec111445e962022-12-22T01:17:33ZengMDPI AGMolecules1420-30492013-09-011810119781199510.3390/molecules181011978Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole SulfonamidesAidil Abdul HamidEkhlass M. TahaZanariah AbdullahRaied M. ShakirYatimah AliasNassir N. Al-MohammedSeveral new substituted sulfonamide compounds were synthesized and their structures were confirmed by 1H-NMR, 13C-NMR, FT-IR, and mass spectroscopy. The antibacterial activities of the synthesized compounds were screened against standard strains of six Gram positive and four Gram negative bacteria using the microbroth dilution assay. Most of the compounds studied showed promising activities against both types of bacteria.http://www.mdpi.com/1420-3049/18/10/11978sulfonamide4-methylbenzenesulfonamide4-nitrobenzenesulfonamide4-methoxybenzenesulfonamideimidazolebenzimidazoleantibacterial activity |
| spellingShingle | Aidil Abdul Hamid Ekhlass M. Taha Zanariah Abdullah Raied M. Shakir Yatimah Alias Nassir N. Al-Mohammed Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole Sulfonamides Molecules sulfonamide 4-methylbenzenesulfonamide 4-nitrobenzenesulfonamide 4-methoxybenzenesulfonamide imidazole benzimidazole antibacterial activity |
| title | Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole Sulfonamides |
| title_full | Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole Sulfonamides |
| title_fullStr | Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole Sulfonamides |
| title_full_unstemmed | Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole Sulfonamides |
| title_short | Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole Sulfonamides |
| title_sort | synthesis and antibacterial evaluation of some novel imidazole and benzimidazole sulfonamides |
| topic | sulfonamide 4-methylbenzenesulfonamide 4-nitrobenzenesulfonamide 4-methoxybenzenesulfonamide imidazole benzimidazole antibacterial activity |
| url | http://www.mdpi.com/1420-3049/18/10/11978 |
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