Microvesicles expressing adenosinergic ectoenzymes and their potential role in modulating bone marrow infiltration by neuroblastoma cells

Microvesicles expressing adenosinergic ectoenzymes and their potential role in modulating bone marrow infiltration by neuroblastoma cells

Metastatic diffusion of Neuroblastoma (NB) cells in the bone marrow (BM) represents the most negative prognostic factors for NB patients. Multiple immune escape mechanisms are postulated as responsible. Our working hypothesis is that adenosine (ADO), an immunosuppressive molecule along with the ecto...

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Bibliographic Details
Main Authors: Fabio Morandi, Danilo Marimpietri, Alberto L. Horenstein, Maria Valeria Corrias, Fabio Malavasi
Format: Article
Language:English
Published: Taylor & Francis Group 2019-05-01
Series:OncoImmunology
Subjects:
neuroblastoma
metastasis
bone marrow
adenosine
microvesicles
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1574198

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