TGF-β Blockade Reduces Mortality and Metabolic Changes in a Validated Murine Model of Pancreatic Cancer Cachexia.
Cancer cachexia is a debilitating condition characterized by a combination of anorexia, muscle wasting, weight loss, and malnutrition. This condition affects an overwhelming majority of patients with pancreatic cancer and is a primary cause of cancer-related death. However, few, if any, effective th...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
格式: | Article |
語言: | English |
出版: |
Public Library of Science (PLoS)
2015-01-01
|
叢編: | PLoS ONE |
在線閱讀: | https://doi.org/10.1371/journal.pone.0132786 |