Investigations on the Aetiology and Antibiotic Management of Neonatal Septicemia

This is a prospective study aimed in identifying the latest aetiological factors of neonatal sepsis in Dr. Cipto General Hospital, Jakarta, and investigating the efficacy of antibiotics treatment especially with ceftriaxone. This study revealed that the present main causative microorganisms are a...

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Main Author: Hans Eldih Monintja
Format: Article
Language:English
Published: Indonesian Pediatric Society Publishing House 2019-07-01
Series:Paediatrica Indonesiana
Subjects:
Online Access:https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2232
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author Hans Eldih Monintja
author_facet Hans Eldih Monintja
author_sort Hans Eldih Monintja
collection DOAJ
description This is a prospective study aimed in identifying the latest aetiological factors of neonatal sepsis in Dr. Cipto General Hospital, Jakarta, and investigating the efficacy of antibiotics treatment especially with ceftriaxone. This study revealed that the present main causative microorganisms are as follows: Pseudomonas, Klebsiella and E. coli. The case fatality rates being: (1) Standard treatment with ampicillin and gentamycin: 80.9%, (2) S(andard treatment with consomittant ceftriaxone: 20%, (3) Ceftriaxone: 9,52%. It seems that in facing neonatal septicemia, the initial antibiotic should be the third generation cephalosporine. The second choice is chloramphenicol. However, the causative agent and the sensitivity test should be monitored regularly.
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spelling doaj.art-b800319a40854b118b3842284d03be112022-12-22T02:09:36ZengIndonesian Pediatric Society Publishing HousePaediatrica Indonesiana0030-93112338-476X2019-07-01285-61051510.14238/pi28.5-6.1988.105-152232Investigations on the Aetiology and Antibiotic Management of Neonatal SepticemiaHans Eldih Monintja0Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, JakartaThis is a prospective study aimed in identifying the latest aetiological factors of neonatal sepsis in Dr. Cipto General Hospital, Jakarta, and investigating the efficacy of antibiotics treatment especially with ceftriaxone. This study revealed that the present main causative microorganisms are as follows: Pseudomonas, Klebsiella and E. coli. The case fatality rates being: (1) Standard treatment with ampicillin and gentamycin: 80.9%, (2) S(andard treatment with consomittant ceftriaxone: 20%, (3) Ceftriaxone: 9,52%. It seems that in facing neonatal septicemia, the initial antibiotic should be the third generation cephalosporine. The second choice is chloramphenicol. However, the causative agent and the sensitivity test should be monitored regularly.https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2232neonatal septicemia; antibiotic; ceftriaxone; pseudomonas
spellingShingle Hans Eldih Monintja
Investigations on the Aetiology and Antibiotic Management of Neonatal Septicemia
Paediatrica Indonesiana
neonatal septicemia; antibiotic; ceftriaxone; pseudomonas
title Investigations on the Aetiology and Antibiotic Management of Neonatal Septicemia
title_full Investigations on the Aetiology and Antibiotic Management of Neonatal Septicemia
title_fullStr Investigations on the Aetiology and Antibiotic Management of Neonatal Septicemia
title_full_unstemmed Investigations on the Aetiology and Antibiotic Management of Neonatal Septicemia
title_short Investigations on the Aetiology and Antibiotic Management of Neonatal Septicemia
title_sort investigations on the aetiology and antibiotic management of neonatal septicemia
topic neonatal septicemia; antibiotic; ceftriaxone; pseudomonas
url https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2232
work_keys_str_mv AT hanseldihmonintja investigationsontheaetiologyandantibioticmanagementofneonatalsepticemia