Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis

The results of a clinical study showing the importance of surfactant proteins A and D in assessing the activity and progression of idiopathic pulmonary fibrosis and chronic lung sarcoidosis are presented. Aim. To study the clinical significance of SP-A, SP-D in assessing the activity of idiopathic p...

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Main Authors: V D Beketov, M V Lebedeva, N A Mukhin, A G Serova, A B Ponomarev, E N Popova, A Sh Yanakaeva, V A Solomka, A V Kondrashov, D V Konovalov
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2018-03-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/32731/pdf
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author V D Beketov
M V Lebedeva
N A Mukhin
A G Serova
A B Ponomarev
E N Popova
A Sh Yanakaeva
V A Solomka
A V Kondrashov
D V Konovalov
author_facet V D Beketov
M V Lebedeva
N A Mukhin
A G Serova
A B Ponomarev
E N Popova
A Sh Yanakaeva
V A Solomka
A V Kondrashov
D V Konovalov
author_sort V D Beketov
collection DOAJ
description The results of a clinical study showing the importance of surfactant proteins A and D in assessing the activity and progression of idiopathic pulmonary fibrosis and chronic lung sarcoidosis are presented. Aim. To study the clinical significance of SP-A, SP-D in assessing the activity of idiopathic pulmonary fibrosis and sarcoidosis. We examined 81 patients with morphologically confirmed diagnoses of idiopathic pulmonary fibrosis (ILF) and sarcoidosis, a control group of 20 healthy individuals. The MSCT of the thoracic organs of the chest was performed, the diffusivity of the lungs was examined, oxygen saturation was determined. In the serum, the surfactant proteins SP-A and SP-D were determined by the enzyme-linked immunosorbent assay. Results. A significant increase in SP-A and SP-D (p
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spelling doaj.art-b800341f99d64a179cdb5f487b77dfff2022-12-22T00:02:48Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422018-03-01903424610.26442/terarkh201890342-4629484Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosisV D Beketov0M V Lebedeva1N A Mukhin2A G Serova3A B Ponomarev4E N Popova5A Sh Yanakaeva6V A Solomka7A V Kondrashov8D V Konovalov9Lomonosov Moscow State UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityLomonosov Moscow State University; Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityThe results of a clinical study showing the importance of surfactant proteins A and D in assessing the activity and progression of idiopathic pulmonary fibrosis and chronic lung sarcoidosis are presented. Aim. To study the clinical significance of SP-A, SP-D in assessing the activity of idiopathic pulmonary fibrosis and sarcoidosis. We examined 81 patients with morphologically confirmed diagnoses of idiopathic pulmonary fibrosis (ILF) and sarcoidosis, a control group of 20 healthy individuals. The MSCT of the thoracic organs of the chest was performed, the diffusivity of the lungs was examined, oxygen saturation was determined. In the serum, the surfactant proteins SP-A and SP-D were determined by the enzyme-linked immunosorbent assay. Results. A significant increase in SP-A and SP-D (phttps://ter-arkhiv.ru/0040-3660/article/viewFile/32731/pdfsarcoidosisinterstitial lung diseasespulmonary fibrosissurfactant protein asurfactant protein d
spellingShingle V D Beketov
M V Lebedeva
N A Mukhin
A G Serova
A B Ponomarev
E N Popova
A Sh Yanakaeva
V A Solomka
A V Kondrashov
D V Konovalov
Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis
Терапевтический архив
sarcoidosis
interstitial lung diseases
pulmonary fibrosis
surfactant protein a
surfactant protein d
title Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis
title_full Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis
title_fullStr Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis
title_full_unstemmed Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis
title_short Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis
title_sort clinical significance of the determination of surfactant proteins a and d in assessing the activity of lung sarcoidosis
topic sarcoidosis
interstitial lung diseases
pulmonary fibrosis
surfactant protein a
surfactant protein d
url https://ter-arkhiv.ru/0040-3660/article/viewFile/32731/pdf
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