Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis
The results of a clinical study showing the importance of surfactant proteins A and D in assessing the activity and progression of idiopathic pulmonary fibrosis and chronic lung sarcoidosis are presented. Aim. To study the clinical significance of SP-A, SP-D in assessing the activity of idiopathic p...
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Language: | Russian |
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"Consilium Medicum" Publishing house
2018-03-01
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Series: | Терапевтический архив |
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Online Access: | https://ter-arkhiv.ru/0040-3660/article/viewFile/32731/pdf |
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author | V D Beketov M V Lebedeva N A Mukhin A G Serova A B Ponomarev E N Popova A Sh Yanakaeva V A Solomka A V Kondrashov D V Konovalov |
author_facet | V D Beketov M V Lebedeva N A Mukhin A G Serova A B Ponomarev E N Popova A Sh Yanakaeva V A Solomka A V Kondrashov D V Konovalov |
author_sort | V D Beketov |
collection | DOAJ |
description | The results of a clinical study showing the importance of surfactant proteins A and D in assessing the activity and progression of idiopathic pulmonary fibrosis and chronic lung sarcoidosis are presented. Aim. To study the clinical significance of SP-A, SP-D in assessing the activity of idiopathic pulmonary fibrosis and sarcoidosis. We examined 81 patients with morphologically confirmed diagnoses of idiopathic pulmonary fibrosis (ILF) and sarcoidosis, a control group of 20 healthy individuals. The MSCT of the thoracic organs of the chest was performed, the diffusivity of the lungs was examined, oxygen saturation was determined. In the serum, the surfactant proteins SP-A and SP-D were determined by the enzyme-linked immunosorbent assay. Results. A significant increase in SP-A and SP-D (p |
first_indexed | 2024-12-13T02:19:46Z |
format | Article |
id | doaj.art-b800341f99d64a179cdb5f487b77dfff |
institution | Directory Open Access Journal |
issn | 0040-3660 2309-5342 |
language | Russian |
last_indexed | 2024-12-13T02:19:46Z |
publishDate | 2018-03-01 |
publisher | "Consilium Medicum" Publishing house |
record_format | Article |
series | Терапевтический архив |
spelling | doaj.art-b800341f99d64a179cdb5f487b77dfff2022-12-22T00:02:48Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422018-03-01903424610.26442/terarkh201890342-4629484Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosisV D Beketov0M V Lebedeva1N A Mukhin2A G Serova3A B Ponomarev4E N Popova5A Sh Yanakaeva6V A Solomka7A V Kondrashov8D V Konovalov9Lomonosov Moscow State UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityLomonosov Moscow State University; Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical UniversityThe results of a clinical study showing the importance of surfactant proteins A and D in assessing the activity and progression of idiopathic pulmonary fibrosis and chronic lung sarcoidosis are presented. Aim. To study the clinical significance of SP-A, SP-D in assessing the activity of idiopathic pulmonary fibrosis and sarcoidosis. We examined 81 patients with morphologically confirmed diagnoses of idiopathic pulmonary fibrosis (ILF) and sarcoidosis, a control group of 20 healthy individuals. The MSCT of the thoracic organs of the chest was performed, the diffusivity of the lungs was examined, oxygen saturation was determined. In the serum, the surfactant proteins SP-A and SP-D were determined by the enzyme-linked immunosorbent assay. Results. A significant increase in SP-A and SP-D (phttps://ter-arkhiv.ru/0040-3660/article/viewFile/32731/pdfsarcoidosisinterstitial lung diseasespulmonary fibrosissurfactant protein asurfactant protein d |
spellingShingle | V D Beketov M V Lebedeva N A Mukhin A G Serova A B Ponomarev E N Popova A Sh Yanakaeva V A Solomka A V Kondrashov D V Konovalov Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis Терапевтический архив sarcoidosis interstitial lung diseases pulmonary fibrosis surfactant protein a surfactant protein d |
title | Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis |
title_full | Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis |
title_fullStr | Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis |
title_full_unstemmed | Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis |
title_short | Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis |
title_sort | clinical significance of the determination of surfactant proteins a and d in assessing the activity of lung sarcoidosis |
topic | sarcoidosis interstitial lung diseases pulmonary fibrosis surfactant protein a surfactant protein d |
url | https://ter-arkhiv.ru/0040-3660/article/viewFile/32731/pdf |
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