Emerging Insights into Molecular Mechanisms of Inflammation in Myelodysplastic Syndromes

Emerging Insights into Molecular Mechanisms of Inflammation in Myelodysplastic Syndromes

Inflammation impacts human hematopoiesis across physiologic and pathologic conditions, as signals derived from the bone marrow microenvironment, such as pro-inflammatory cytokines and chemokines, have been shown to alter hematopoietic stem cell (HSCs) homeostasis. Dysregulated inflammation can skew...

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Bibliographic Details
Main Authors: Veronica Vallelonga, Francesco Gandolfi, Francesca Ficara, Matteo Giovanni Della Porta, Serena Ghisletti
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomedicines
Subjects:
inflammation
hematopoiesis
MDS
HSC
sc-RNAseq
sc-ATACseq
Online Access:https://www.mdpi.com/2227-9059/11/10/2613

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