Sexually dimorphic extracellular vesicle responses after chronic spinal cord injury are associated with neuroinflammation and neurodegeneration in the aged brain

Sexually dimorphic extracellular vesicle responses after chronic spinal cord injury are associated with neuroinflammation and neurodegeneration in the aged brain

Abstract Background Medical advances have made it increasingly possible for spinal cord injury (SCI) survivors to survive decades after the insult. But how SCI affects aging changes and aging impacts the injury process have received limited attention. Extracellular vesicles (EVs) are recognized as c...

Full description

Bibliographic Details
Main Authors: Yun Li, Niaz Khan, Rodney M. Ritzel, Zhuofan Lei, Samantha Allen, Alan I. Faden, Junfang Wu
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Neuroinflammation
Subjects:
Chronic spinal cord injury
Extracellular vesicles
Biological sex
Brain transcriptional changes
microRNAs
EVs content
Online Access:https://doi.org/10.1186/s12974-023-02881-z

Internet

https://doi.org/10.1186/s12974-023-02881-z

Similar Items