Six gene and TH2 signature expression in endobronchial biopsies of participants with asthma

Six gene and TH2 signature expression in endobronchial biopsies of participants with asthma

Abstract Background Both the six gene signature (6GS: CPA3, DNASE1L3, CLC, IL1B, ALPL, and CXCR2) and T‐helper 2 signature (TH2S: CLCA1, SERPINB2, and POSTN) are proposed as biomarkers in the identification of inflammatory phenotypes of asthma in induced sputum and epithelial brushings, respectively...

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Bibliographic Details
Main Authors: Stephany Sánchez‐Ovando, Katherine J. Baines, Daniel Barker, Peter A. Wark, Jodie L. Simpson
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Immunity, Inflammation and Disease
Subjects:
asthma
endobronchial biopsy
inflammation
inflammatory phenotypes
Online Access:https://doi.org/10.1002/iid3.282

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