Cytological effects in lymph nodes of abdominal lymphodissection zone after intraoperative photodynamic therapy of gastrointestinal cancers

Cytological studies on lymph nodes of abdominal lymphodissection zone after local intraoperative photodynamic therapy (IOPDT) of gastrointestinal cancers were carried out. As a result of the PDT, the metastatic cells are destroyed, their cytoplasmic membranes and the cytoplasm disappears, leaving be...

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Main Authors: V. Yu. Kravtsov, E. S. Pirozhenko, K. V. Pavelec, M. A. Protchenkov, U. A. Drozd
Format: Article
Language:Russian
Published: Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" 2019-01-01
Series:Biomedical Photonics
Subjects:
Online Access:https://www.pdt-journal.com/jour/article/view/270
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author V. Yu. Kravtsov
E. S. Pirozhenko
K. V. Pavelec
M. A. Protchenkov
U. A. Drozd
author_facet V. Yu. Kravtsov
E. S. Pirozhenko
K. V. Pavelec
M. A. Protchenkov
U. A. Drozd
author_sort V. Yu. Kravtsov
collection DOAJ
description Cytological studies on lymph nodes of abdominal lymphodissection zone after local intraoperative photodynamic therapy (IOPDT) of gastrointestinal cancers were carried out. As a result of the PDT, the metastatic cells are destroyed, their cytoplasmic membranes and the cytoplasm disappears, leaving behind interphase nuclei ("naked nuclei") (p<0,0001). Cytological confrmation of apoptosis (the presence of apoptotic bodies) in metastatic lymph nodes after IOPDT sessions on the lymph nodes of the abdominal lymphodissection zone is also presented.
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language Russian
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publisher Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"
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spelling doaj.art-b804e37b514d46a1807c30acc1cdb12f2023-03-13T07:12:30ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322019-01-0174111510.24931/2413-9432-2018-7-4-11-15150Cytological effects in lymph nodes of abdominal lymphodissection zone after intraoperative photodynamic therapy of gastrointestinal cancersV. Yu. Kravtsov0E. S. Pirozhenko1K. V. Pavelec2M. A. Protchenkov3U. A. Drozd4Военно-медицинская академия им. С.М. Кирова, Санкт-Петербург; Северо-Западный государственный медицинский университет имени И.И. Мечникова, Санкт-ПетербургВоенно-медицинская академия им. С.М. Кирова, Санкт-ПетербургСеверо-Западный государственный медицинский университет имени И.И. Мечникова, Санкт-Петербург; Санкт-Петербургский государственный педиатрический медицинский университет, Санкт-Петербург; Городская Мариинская больница, Санкт-ПетербургСеверо-Западный государственный медицинский университет имени И.И. Мечникова, Санкт-Петербург; Городская Мариинская больница, Санкт-ПетербургСанкт-Петербургский государственный педиатрический медицинский университет, Санкт-ПетербургCytological studies on lymph nodes of abdominal lymphodissection zone after local intraoperative photodynamic therapy (IOPDT) of gastrointestinal cancers were carried out. As a result of the PDT, the metastatic cells are destroyed, their cytoplasmic membranes and the cytoplasm disappears, leaving behind interphase nuclei ("naked nuclei") (p<0,0001). Cytological confrmation of apoptosis (the presence of apoptotic bodies) in metastatic lymph nodes after IOPDT sessions on the lymph nodes of the abdominal lymphodissection zone is also presented.https://www.pdt-journal.com/jour/article/view/270фотодинамическая терапияцитопатологияинтерфазные ядраапоптозрадахлоринфотодитазин
spellingShingle V. Yu. Kravtsov
E. S. Pirozhenko
K. V. Pavelec
M. A. Protchenkov
U. A. Drozd
Cytological effects in lymph nodes of abdominal lymphodissection zone after intraoperative photodynamic therapy of gastrointestinal cancers
Biomedical Photonics
фотодинамическая терапия
цитопатология
интерфазные ядра
апоптоз
радахлорин
фотодитазин
title Cytological effects in lymph nodes of abdominal lymphodissection zone after intraoperative photodynamic therapy of gastrointestinal cancers
title_full Cytological effects in lymph nodes of abdominal lymphodissection zone after intraoperative photodynamic therapy of gastrointestinal cancers
title_fullStr Cytological effects in lymph nodes of abdominal lymphodissection zone after intraoperative photodynamic therapy of gastrointestinal cancers
title_full_unstemmed Cytological effects in lymph nodes of abdominal lymphodissection zone after intraoperative photodynamic therapy of gastrointestinal cancers
title_short Cytological effects in lymph nodes of abdominal lymphodissection zone after intraoperative photodynamic therapy of gastrointestinal cancers
title_sort cytological effects in lymph nodes of abdominal lymphodissection zone after intraoperative photodynamic therapy of gastrointestinal cancers
topic фотодинамическая терапия
цитопатология
интерфазные ядра
апоптоз
радахлорин
фотодитазин
url https://www.pdt-journal.com/jour/article/view/270
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