Deblurring, artifact-free optical coherence tomography with deconvolution-random phase modulation
Deconvolution is a commonly employed technique for enhancing image quality in optical imaging methods. Unfortunately, its application in optical coherence tomography (OCT) is often hindered by sensitivity to noise, which leads to additive ringing artifacts. These artifacts considerably degrade the q...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Editorial Office of Opto-Electronic Journals, Institute of Optics and Electronics, CAS, China
2024-01-01
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| Series: | Opto-Electronic Science |
| Subjects: | |
| Online Access: | https://www.oejournal.org/article/doi/10.29026/oes.2024.230020 |
| _version_ | 1827316743567048704 |
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| author | Xin Ge Si Chen Kan Lin Guangming Ni En Bo Lulu Wang Linbo Liu |
| author_facet | Xin Ge Si Chen Kan Lin Guangming Ni En Bo Lulu Wang Linbo Liu |
| author_sort | Xin Ge |
| collection | DOAJ |
| description | Deconvolution is a commonly employed technique for enhancing image quality in optical imaging methods. Unfortunately, its application in optical coherence tomography (OCT) is often hindered by sensitivity to noise, which leads to additive ringing artifacts. These artifacts considerably degrade the quality of deconvolved images, thereby limiting its effectiveness in OCT imaging. In this study, we propose a framework that integrates numerical random phase masks into the deconvolution process, effectively eliminating these artifacts and enhancing image clarity. The optimized joint operation of an iterative Richardson-Lucy deconvolution and numerical synthesis of random phase masks (RPM), termed as Deconv-RPM, enables a 2.5-fold reduction in full width at half-maximum (FWHM). We demonstrate that the Deconv-RPM method significantly enhances image clarity, allowing for the discernment of previously unresolved cellular-level details in nonkeratinized epithelial cells ex vivo and moving blood cells in vivo. |
| first_indexed | 2024-04-24T23:20:54Z |
| format | Article |
| id | doaj.art-b80728f99a14403b9424da0bb9e8043e |
| institution | Directory Open Access Journal |
| issn | 2097-0382 |
| language | English |
| last_indexed | 2024-04-24T23:20:54Z |
| publishDate | 2024-01-01 |
| publisher | Editorial Office of Opto-Electronic Journals, Institute of Optics and Electronics, CAS, China |
| record_format | Article |
| series | Opto-Electronic Science |
| spelling | doaj.art-b80728f99a14403b9424da0bb9e8043e2024-03-16T12:15:06ZengEditorial Office of Opto-Electronic Journals, Institute of Optics and Electronics, CAS, ChinaOpto-Electronic Science2097-03822024-01-013111210.29026/oes.2024.230020oes-2023-0020Deblurring, artifact-free optical coherence tomography with deconvolution-random phase modulationXin Ge0Si Chen1Kan Lin2Guangming Ni3En Bo4Lulu Wang5Linbo Liu6School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeSchool of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeSchool of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeSchool of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu 610054, ChinaSchool of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeSchool of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeSchool of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeDeconvolution is a commonly employed technique for enhancing image quality in optical imaging methods. Unfortunately, its application in optical coherence tomography (OCT) is often hindered by sensitivity to noise, which leads to additive ringing artifacts. These artifacts considerably degrade the quality of deconvolved images, thereby limiting its effectiveness in OCT imaging. In this study, we propose a framework that integrates numerical random phase masks into the deconvolution process, effectively eliminating these artifacts and enhancing image clarity. The optimized joint operation of an iterative Richardson-Lucy deconvolution and numerical synthesis of random phase masks (RPM), termed as Deconv-RPM, enables a 2.5-fold reduction in full width at half-maximum (FWHM). We demonstrate that the Deconv-RPM method significantly enhances image clarity, allowing for the discernment of previously unresolved cellular-level details in nonkeratinized epithelial cells ex vivo and moving blood cells in vivo.https://www.oejournal.org/article/doi/10.29026/oes.2024.230020deconvolutionrandom phase masksdeblurring |
| spellingShingle | Xin Ge Si Chen Kan Lin Guangming Ni En Bo Lulu Wang Linbo Liu Deblurring, artifact-free optical coherence tomography with deconvolution-random phase modulation Opto-Electronic Science deconvolution random phase masks deblurring |
| title | Deblurring, artifact-free optical coherence tomography with deconvolution-random phase modulation |
| title_full | Deblurring, artifact-free optical coherence tomography with deconvolution-random phase modulation |
| title_fullStr | Deblurring, artifact-free optical coherence tomography with deconvolution-random phase modulation |
| title_full_unstemmed | Deblurring, artifact-free optical coherence tomography with deconvolution-random phase modulation |
| title_short | Deblurring, artifact-free optical coherence tomography with deconvolution-random phase modulation |
| title_sort | deblurring artifact free optical coherence tomography with deconvolution random phase modulation |
| topic | deconvolution random phase masks deblurring |
| url | https://www.oejournal.org/article/doi/10.29026/oes.2024.230020 |
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