Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients

Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients Abstract: Background: Doppler ultrasonography is the best tool for assessment of transplanted kidneys’ vascular status. On the other hand cyclosporine A widely con...

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Main Authors: zohreh makki, sarir nazemi, Ahmad Enhesari, Jalal Azmandian, saeid Mardpur
Format: Article
Language:fas
Published: Jahrom University of Medical Sciences 2015-04-01
Series:فصلنامه دانشگاه علوم پزشکی جهرم
Subjects:
Online Access:http://jmj.jums.ac.ir/article-1-466-en.html
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author zohreh makki
sarir nazemi
Ahmad Enhesari
Jalal Azmandian
saeid Mardpur
author_facet zohreh makki
sarir nazemi
Ahmad Enhesari
Jalal Azmandian
saeid Mardpur
author_sort zohreh makki
collection DOAJ
description Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients Abstract: Background: Doppler ultrasonography is the best tool for assessment of transplanted kidneys’ vascular status. On the other hand cyclosporine A widely consume to prevent graft rejection, has some vasoconstriction effects influence the Doppler parameters. To date, there has been little agreement on this effect. This paper will focus on the evaluation of whether cyclosporine A was affect the Doppler parameters. Materials and methods: A cross-sectional study was performed on 31 stable patients, between 6-18 months after transplantation. All patients were received immunocompromised treatment including cyclosporine A. Interarenal Doppler indices, resistive index (RI) and pulsatility index and end diastolic velocity (EDV) and peak systolic velocity (PSV) were measured at interlobar artery level before and 2 hour after (peak serum level) the oral intake of cyclosporine A. Data analysis were made by SPSS software to estimate the influence of cyclosporine A on the Doppler parameters. Results: compared with Doppler parameters before and 2hour after cyclosporine A, among patients with mean serum creatinin levels about 1.3, values remained unchanged. Conclusion: In this study, consumption of cyclosporine A dose not lead to acute rise in ultrasonographic Doppler indices.
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spelling doaj.art-b8093c183fa644818de0c8e5e1a214202022-12-22T01:02:50ZfasJahrom University of Medical Sciencesفصلنامه دانشگاه علوم پزشکی جهرم2008-79932008-84422015-04-011315762Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipientszohreh makki0sarir nazemi1Ahmad Enhesari2Jalal Azmandian3saeid Mardpur4 Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients Abstract: Background: Doppler ultrasonography is the best tool for assessment of transplanted kidneys’ vascular status. On the other hand cyclosporine A widely consume to prevent graft rejection, has some vasoconstriction effects influence the Doppler parameters. To date, there has been little agreement on this effect. This paper will focus on the evaluation of whether cyclosporine A was affect the Doppler parameters. Materials and methods: A cross-sectional study was performed on 31 stable patients, between 6-18 months after transplantation. All patients were received immunocompromised treatment including cyclosporine A. Interarenal Doppler indices, resistive index (RI) and pulsatility index and end diastolic velocity (EDV) and peak systolic velocity (PSV) were measured at interlobar artery level before and 2 hour after (peak serum level) the oral intake of cyclosporine A. Data analysis were made by SPSS software to estimate the influence of cyclosporine A on the Doppler parameters. Results: compared with Doppler parameters before and 2hour after cyclosporine A, among patients with mean serum creatinin levels about 1.3, values remained unchanged. Conclusion: In this study, consumption of cyclosporine A dose not lead to acute rise in ultrasonographic Doppler indices.http://jmj.jums.ac.ir/article-1-466-en.htmltransplanted kidneyultrasonographycross-sectional studycyclosporine a
spellingShingle zohreh makki
sarir nazemi
Ahmad Enhesari
Jalal Azmandian
saeid Mardpur
Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients
فصلنامه دانشگاه علوم پزشکی جهرم
transplanted kidney
ultrasonography
cross-sectional study
cyclosporine a
title Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients
title_full Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients
title_fullStr Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients
title_full_unstemmed Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients
title_short Comparison of Doppler ultrasonographic indices before and after cyclosporine A peak serum level in stable kidney transplanted recipients
title_sort comparison of doppler ultrasonographic indices before and after cyclosporine a peak serum level in stable kidney transplanted recipients
topic transplanted kidney
ultrasonography
cross-sectional study
cyclosporine a
url http://jmj.jums.ac.ir/article-1-466-en.html
work_keys_str_mv AT zohrehmakki comparisonofdopplerultrasonographicindicesbeforeandaftercyclosporineapeakserumlevelinstablekidneytransplantedrecipients
AT sarirnazemi comparisonofdopplerultrasonographicindicesbeforeandaftercyclosporineapeakserumlevelinstablekidneytransplantedrecipients
AT ahmadenhesari comparisonofdopplerultrasonographicindicesbeforeandaftercyclosporineapeakserumlevelinstablekidneytransplantedrecipients
AT jalalazmandian comparisonofdopplerultrasonographicindicesbeforeandaftercyclosporineapeakserumlevelinstablekidneytransplantedrecipients
AT saeidmardpur comparisonofdopplerultrasonographicindicesbeforeandaftercyclosporineapeakserumlevelinstablekidneytransplantedrecipients