Linear-like polypeptide-based micelle with pH-sensitive detachable PEG to deliver dimeric camptothecin for cancer therapy

Nano drug delivery systems have made significant progress in delivering anticancer drugs camptothecin (CPT). However, many challenges for CPT delivery remain, including low drug loading efficiency, premature drug leakage, and poor cellular internalization. Herein, we report a novel dual-sensitive po...

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Hlavní autoři: Ka Hong Wong, Zhaopei Guo, Di Jiang, Xingzhi Zhou, Lizhu Lin, Denggao Zhao, Meiwan Chen
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2023-01-01
Edice:Asian Journal of Pharmaceutical Sciences
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S1818087622001222