Linear-like polypeptide-based micelle with pH-sensitive detachable PEG to deliver dimeric camptothecin for cancer therapy

Nano drug delivery systems have made significant progress in delivering anticancer drugs camptothecin (CPT). However, many challenges for CPT delivery remain, including low drug loading efficiency, premature drug leakage, and poor cellular internalization. Herein, we report a novel dual-sensitive po...

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Main Authors: Ka Hong Wong, Zhaopei Guo, Di Jiang, Xingzhi Zhou, Lizhu Lin, Denggao Zhao, Meiwan Chen
格式: 文件
语言:English
出版: Elsevier 2023-01-01
丛编:Asian Journal of Pharmaceutical Sciences
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在线阅读:http://www.sciencedirect.com/science/article/pii/S1818087622001222