Physiological Effects of Bioactive Compounds Derived from Whole Grains on Cardiovascular and Metabolic Diseases
Cardiovascular diseases are a global health burden with an increasing prevalence. In addition, various metabolic diseases, such as obesity, diabetes, and hypertension are associated with a higher risk of cardiovascular diseases. Dietary strategies based on healthy foods have been suggested for the p...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/12/2/658 |
| _version_ | 1797496122023870464 |
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| author | Sangwon Chung Jin-Taek Hwang Soo-Hyun Park |
| author_facet | Sangwon Chung Jin-Taek Hwang Soo-Hyun Park |
| author_sort | Sangwon Chung |
| collection | DOAJ |
| description | Cardiovascular diseases are a global health burden with an increasing prevalence. In addition, various metabolic diseases, such as obesity, diabetes, and hypertension are associated with a higher risk of cardiovascular diseases. Dietary strategies based on healthy foods have been suggested for the prevention or improvement of cardiovascular and metabolic diseases. Grains are the most widely consumed food worldwide, and the preventive effects of whole grains (e.g., oats, barley, and buckwheat) on metabolic diseases have been reported. The germ and bran of grains are rich in compounds, including phytochemicals, vitamins, minerals, and dietary fiber, and these compounds are effective in preventing and improving cardiovascular and metabolic diseases. Thus, this review describes the characteristics and functions of bioactive ingredients in whole grains, focusing on mechanisms by which polyphenols, antioxidants, and dietary fiber contribute to cardiovascular and metabolic diseases, based on preclinical and clinical studies. There is clear evidence for the broad preventive and therapeutic effects of whole grains, supporting the value of early dietary intervention. |
| first_indexed | 2024-03-10T01:59:08Z |
| format | Article |
| id | doaj.art-b80eb8040e7644249844449dd2dcca1a |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T01:59:08Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-b80eb8040e7644249844449dd2dcca1a2023-11-23T12:50:38ZengMDPI AGApplied Sciences2076-34172022-01-0112265810.3390/app12020658Physiological Effects of Bioactive Compounds Derived from Whole Grains on Cardiovascular and Metabolic DiseasesSangwon Chung0Jin-Taek Hwang1Soo-Hyun Park2Personalized Diet Research Group, Food Functionality Research Division, Korea Food Research Institute, Wanju-gun 55365, KoreaPersonalized Diet Research Group, Food Functionality Research Division, Korea Food Research Institute, Wanju-gun 55365, KoreaPersonalized Diet Research Group, Food Functionality Research Division, Korea Food Research Institute, Wanju-gun 55365, KoreaCardiovascular diseases are a global health burden with an increasing prevalence. In addition, various metabolic diseases, such as obesity, diabetes, and hypertension are associated with a higher risk of cardiovascular diseases. Dietary strategies based on healthy foods have been suggested for the prevention or improvement of cardiovascular and metabolic diseases. Grains are the most widely consumed food worldwide, and the preventive effects of whole grains (e.g., oats, barley, and buckwheat) on metabolic diseases have been reported. The germ and bran of grains are rich in compounds, including phytochemicals, vitamins, minerals, and dietary fiber, and these compounds are effective in preventing and improving cardiovascular and metabolic diseases. Thus, this review describes the characteristics and functions of bioactive ingredients in whole grains, focusing on mechanisms by which polyphenols, antioxidants, and dietary fiber contribute to cardiovascular and metabolic diseases, based on preclinical and clinical studies. There is clear evidence for the broad preventive and therapeutic effects of whole grains, supporting the value of early dietary intervention.https://www.mdpi.com/2076-3417/12/2/658whole grainbioactive compoundscardiovascular diseasemetabolic disease |
| spellingShingle | Sangwon Chung Jin-Taek Hwang Soo-Hyun Park Physiological Effects of Bioactive Compounds Derived from Whole Grains on Cardiovascular and Metabolic Diseases Applied Sciences whole grain bioactive compounds cardiovascular disease metabolic disease |
| title | Physiological Effects of Bioactive Compounds Derived from Whole Grains on Cardiovascular and Metabolic Diseases |
| title_full | Physiological Effects of Bioactive Compounds Derived from Whole Grains on Cardiovascular and Metabolic Diseases |
| title_fullStr | Physiological Effects of Bioactive Compounds Derived from Whole Grains on Cardiovascular and Metabolic Diseases |
| title_full_unstemmed | Physiological Effects of Bioactive Compounds Derived from Whole Grains on Cardiovascular and Metabolic Diseases |
| title_short | Physiological Effects of Bioactive Compounds Derived from Whole Grains on Cardiovascular and Metabolic Diseases |
| title_sort | physiological effects of bioactive compounds derived from whole grains on cardiovascular and metabolic diseases |
| topic | whole grain bioactive compounds cardiovascular disease metabolic disease |
| url | https://www.mdpi.com/2076-3417/12/2/658 |
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