Assessing the Immunomodulatory Effect of Size on the Uptake and Immunogenicity of Influenza- and Hepatitis B Subunit Vaccines In Vitro
Viral subunit vaccines are a safer and more tolerable alternative to whole inactivated virus vaccines. However, they often come with limited efficacy, necessitating the use of adjuvants. Using free and particle-bound viral antigens, we assessed whether size affects the uptake of those antigens by hu...
Main Authors: | Rick Heida, Philip A. Born, Gabriela Tapia-Calle, Henderik W. Frijlink, Anna Salvati, Anke L. W. Huckriede, Wouter L. J. Hinrichs |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-07-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/15/7/887 |
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