Effect of modified extraperitoneal laparoscopic total intrafascial radical prostatectomy on clinical efficacy for prostate cancer patients

The effective surgical treatments of localized prostate cancer patients were explored. 90 prostate cancer patients admitted to our hospital were selected as study subjects. They were divided into research (treated by modified extraperitoneal total intrafascial laparoscopic radical prostatectomy)...

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Main Authors: Dan Yuan, Kang Li, Yu Wang, Long Huang, Mingsong Wang, Kang Jia
Format: Article
Language:English
Published: MRE Press 2023-07-01
Series:Journal of Men's Health
Subjects:
Online Access:https://oss.jomh.org/files/article/20230731-54/pdf/JOMH2023030701.pdf
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author Dan Yuan
Kang Li
Yu Wang
Long Huang
Mingsong Wang
Kang Jia
author_facet Dan Yuan
Kang Li
Yu Wang
Long Huang
Mingsong Wang
Kang Jia
author_sort Dan Yuan
collection DOAJ
description The effective surgical treatments of localized prostate cancer patients were explored. 90 prostate cancer patients admitted to our hospital were selected as study subjects. They were divided into research (treated by modified extraperitoneal total intrafascial laparoscopic radical prostatectomy) and control (treated by extraperitoneal laparoscopic radical prostatectomy) groups by random number table method, having 45 cases each. The operation time, bleeding volume, drainage time, hospitalization time, vascular endothelial stimulation index, urinary control function, erectile function, complications, and recurrence were monitored and compared. No significant difference was found between the two groups in clinical operation related indexes. On 3rd and 7th days after operation, VEGF (Vascular Endothelial Growth Factor) and IGF-I (Insulin-like Growth Factor 1) in research group were lower than those in control (p < 0.005). The urine control rate and erectile function normal rate in research group were higher than those in control (p < 0.005). Modified extraperitoneal laparoscopic total intrafascial radical prostatectomy reduced the degrees of trauma and irritation in the operation of prostate cancer patients. Moreover, during the observation period, it improved the postoperative urinary control and erectile function of patients and reduced the complications. Thus, this method has the worth of clinical promotion and application.
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spelling doaj.art-b8121f13bd2e44c2b40c1c9b9ffc86672024-02-03T13:22:46ZengMRE PressJournal of Men's Health1875-68592023-07-01197869210.22514/jomh.2023.060S1875-6867(23)00029-5Effect of modified extraperitoneal laparoscopic total intrafascial radical prostatectomy on clinical efficacy for prostate cancer patientsDan Yuan0Kang Li1Yu Wang2Long Huang3Mingsong Wang4Kang Jia5Department of Urology, 363 Hospital, 610041 Chengdu, Sichuan, ChinaDepartment of Urology, 363 Hospital, 610041 Chengdu, Sichuan, ChinaDepartment of Urology, 363 Hospital, 610041 Chengdu, Sichuan, ChinaDepartment of Urology, 363 Hospital, 610041 Chengdu, Sichuan, ChinaDepartment of Urology, 363 Hospital, 610041 Chengdu, Sichuan, ChinaDepartment of Urology, 363 Hospital, 610041 Chengdu, Sichuan, ChinaThe effective surgical treatments of localized prostate cancer patients were explored. 90 prostate cancer patients admitted to our hospital were selected as study subjects. They were divided into research (treated by modified extraperitoneal total intrafascial laparoscopic radical prostatectomy) and control (treated by extraperitoneal laparoscopic radical prostatectomy) groups by random number table method, having 45 cases each. The operation time, bleeding volume, drainage time, hospitalization time, vascular endothelial stimulation index, urinary control function, erectile function, complications, and recurrence were monitored and compared. No significant difference was found between the two groups in clinical operation related indexes. On 3rd and 7th days after operation, VEGF (Vascular Endothelial Growth Factor) and IGF-I (Insulin-like Growth Factor 1) in research group were lower than those in control (p < 0.005). The urine control rate and erectile function normal rate in research group were higher than those in control (p < 0.005). Modified extraperitoneal laparoscopic total intrafascial radical prostatectomy reduced the degrees of trauma and irritation in the operation of prostate cancer patients. Moreover, during the observation period, it improved the postoperative urinary control and erectile function of patients and reduced the complications. Thus, this method has the worth of clinical promotion and application.https://oss.jomh.org/files/article/20230731-54/pdf/JOMH2023030701.pdfimprovementextraperitoneal laparoscopytotal intrafascial radical prostatectomyprostate cancerclinical efficacy
spellingShingle Dan Yuan
Kang Li
Yu Wang
Long Huang
Mingsong Wang
Kang Jia
Effect of modified extraperitoneal laparoscopic total intrafascial radical prostatectomy on clinical efficacy for prostate cancer patients
Journal of Men's Health
improvement
extraperitoneal laparoscopy
total intrafascial radical prostatectomy
prostate cancer
clinical efficacy
title Effect of modified extraperitoneal laparoscopic total intrafascial radical prostatectomy on clinical efficacy for prostate cancer patients
title_full Effect of modified extraperitoneal laparoscopic total intrafascial radical prostatectomy on clinical efficacy for prostate cancer patients
title_fullStr Effect of modified extraperitoneal laparoscopic total intrafascial radical prostatectomy on clinical efficacy for prostate cancer patients
title_full_unstemmed Effect of modified extraperitoneal laparoscopic total intrafascial radical prostatectomy on clinical efficacy for prostate cancer patients
title_short Effect of modified extraperitoneal laparoscopic total intrafascial radical prostatectomy on clinical efficacy for prostate cancer patients
title_sort effect of modified extraperitoneal laparoscopic total intrafascial radical prostatectomy on clinical efficacy for prostate cancer patients
topic improvement
extraperitoneal laparoscopy
total intrafascial radical prostatectomy
prostate cancer
clinical efficacy
url https://oss.jomh.org/files/article/20230731-54/pdf/JOMH2023030701.pdf
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