Optimal stimulation settings for CMAP scan registrations
<p>Abstract</p> <p>Background</p> <p>The CMAP (Compound Muscle Action Potential) scan is a non-invasive electrodiagnostic tool, which provides a quick and visual assessment of motor unit potentials as electrophysiological components that together constitute the CMAP. Th...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Georg Thieme Verlag KG
2012-06-01
|
| Series: | Journal of Brachial Plexus and Peripheral Nerve Injury |
| Subjects: | |
| Online Access: | http://www.jbppni.com/content/7/1/4 |
| _version_ | 1819053115279671296 |
|---|---|
| author | Maathuis Ellen M Henderson Robert D Drenthen Judith Hutchinson Nicole M Daube Jasper R Blok Joleen H Visser Gerhard H |
| author_facet | Maathuis Ellen M Henderson Robert D Drenthen Judith Hutchinson Nicole M Daube Jasper R Blok Joleen H Visser Gerhard H |
| author_sort | Maathuis Ellen M |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>The CMAP (Compound Muscle Action Potential) scan is a non-invasive electrodiagnostic tool, which provides a quick and visual assessment of motor unit potentials as electrophysiological components that together constitute the CMAP. The CMAP scan records the electrical activity of the muscle (CMAP) in response to transcutaneous stimulation of the motor nerve with gradual changes in stimulus intensity. Large MUs, including those that result from collateral reinnervation, appear in the CMAP scan as so-called steps, i.e., clearly visible jumps in CMAP amplitude. The CMAP scan also provides information on nerve excitability. This study aims to evaluate the influence of the stimulation protocol used on the CMAP scan and its quantification.</p> <p>Methods</p> <p>The stimulus frequency (1, 2 and 3 Hz), duration (0.05, 0.1 and 0.3 ms), or number (300, 500 and 1000 stimuli) in CMAP scans of 23 subjects was systematically varied while the other two parameters were kept constant. Pain was measured by means of a visual analogue scale (VAS). Non-parametric paired tests were used to assess significant differences in excitability and step variables and VAS scores between the different stimulus parameter settings.</p> <p>Results</p> <p>We found no effect of stimulus frequency on CMAP scan variables or VAS scores. Stimulus duration affected excitability variables significantly, with higher stimulus intensity values for shorter stimulus durations. Step variables showed a clear trend towards increasing values with decreasing stimulus number.</p> <p>Conclusions</p> <p>A protocol delivering 500 stimuli at a frequency of 2 Hz with a 0.1 ms pulse duration optimized CMAP scan quantification with a minimum of subject discomfort, artefact and duration of the recording. CMAP scan variables were influenced by stimulus duration and number; hence, these need to be standardized in future studies.</p> |
| first_indexed | 2024-12-21T12:30:36Z |
| format | Article |
| id | doaj.art-b8157cb3e96e434abd60fa588c564baa |
| institution | Directory Open Access Journal |
| issn | 1749-7221 |
| language | English |
| last_indexed | 2024-12-21T12:30:36Z |
| publishDate | 2012-06-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | Journal of Brachial Plexus and Peripheral Nerve Injury |
| spelling | doaj.art-b8157cb3e96e434abd60fa588c564baa2022-12-21T19:04:02ZengGeorg Thieme Verlag KGJournal of Brachial Plexus and Peripheral Nerve Injury1749-72212012-06-0171410.1186/1749-7221-7-4Optimal stimulation settings for CMAP scan registrationsMaathuis Ellen MHenderson Robert DDrenthen JudithHutchinson Nicole MDaube Jasper RBlok Joleen HVisser Gerhard H<p>Abstract</p> <p>Background</p> <p>The CMAP (Compound Muscle Action Potential) scan is a non-invasive electrodiagnostic tool, which provides a quick and visual assessment of motor unit potentials as electrophysiological components that together constitute the CMAP. The CMAP scan records the electrical activity of the muscle (CMAP) in response to transcutaneous stimulation of the motor nerve with gradual changes in stimulus intensity. Large MUs, including those that result from collateral reinnervation, appear in the CMAP scan as so-called steps, i.e., clearly visible jumps in CMAP amplitude. The CMAP scan also provides information on nerve excitability. This study aims to evaluate the influence of the stimulation protocol used on the CMAP scan and its quantification.</p> <p>Methods</p> <p>The stimulus frequency (1, 2 and 3 Hz), duration (0.05, 0.1 and 0.3 ms), or number (300, 500 and 1000 stimuli) in CMAP scans of 23 subjects was systematically varied while the other two parameters were kept constant. Pain was measured by means of a visual analogue scale (VAS). Non-parametric paired tests were used to assess significant differences in excitability and step variables and VAS scores between the different stimulus parameter settings.</p> <p>Results</p> <p>We found no effect of stimulus frequency on CMAP scan variables or VAS scores. Stimulus duration affected excitability variables significantly, with higher stimulus intensity values for shorter stimulus durations. Step variables showed a clear trend towards increasing values with decreasing stimulus number.</p> <p>Conclusions</p> <p>A protocol delivering 500 stimuli at a frequency of 2 Hz with a 0.1 ms pulse duration optimized CMAP scan quantification with a minimum of subject discomfort, artefact and duration of the recording. CMAP scan variables were influenced by stimulus duration and number; hence, these need to be standardized in future studies.</p>http://www.jbppni.com/content/7/1/4CMAP scanStimulus–response curveSettingsStimulus numberStimulus frequencyStimulus duration |
| spellingShingle | Maathuis Ellen M Henderson Robert D Drenthen Judith Hutchinson Nicole M Daube Jasper R Blok Joleen H Visser Gerhard H Optimal stimulation settings for CMAP scan registrations Journal of Brachial Plexus and Peripheral Nerve Injury CMAP scan Stimulus–response curve Settings Stimulus number Stimulus frequency Stimulus duration |
| title | Optimal stimulation settings for CMAP scan registrations |
| title_full | Optimal stimulation settings for CMAP scan registrations |
| title_fullStr | Optimal stimulation settings for CMAP scan registrations |
| title_full_unstemmed | Optimal stimulation settings for CMAP scan registrations |
| title_short | Optimal stimulation settings for CMAP scan registrations |
| title_sort | optimal stimulation settings for cmap scan registrations |
| topic | CMAP scan Stimulus–response curve Settings Stimulus number Stimulus frequency Stimulus duration |
| url | http://www.jbppni.com/content/7/1/4 |
| work_keys_str_mv | AT maathuisellenm optimalstimulationsettingsforcmapscanregistrations AT hendersonrobertd optimalstimulationsettingsforcmapscanregistrations AT drenthenjudith optimalstimulationsettingsforcmapscanregistrations AT hutchinsonnicolem optimalstimulationsettingsforcmapscanregistrations AT daubejasperr optimalstimulationsettingsforcmapscanregistrations AT blokjoleenh optimalstimulationsettingsforcmapscanregistrations AT vissergerhardh optimalstimulationsettingsforcmapscanregistrations |