Quantitative analysis of inter- and intrahemispheric coherence on epileptic electroencephalography signal
When an epileptic seizure occurs, the neuron's activity of the brain is dynamically changed, which affects the connectivity between brain regions. The connectivity of each brain region can be quantified by electroencephalography (EEG) coherence, which measures the statistical correlation betwee...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Journal of Medical Signals and Sensors |
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| Online Access: | http://www.jmssjournal.net/article.asp?issn=2228-7477;year=2022;volume=12;issue=2;spage=145;epage=154;aulast=Wijayanto |
| _version_ | 1818161258688413696 |
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| author | Inung Wijayanto Rudy Hartanto Hanung Adi Nugroho |
| author_facet | Inung Wijayanto Rudy Hartanto Hanung Adi Nugroho |
| author_sort | Inung Wijayanto |
| collection | DOAJ |
| description | When an epileptic seizure occurs, the neuron's activity of the brain is dynamically changed, which affects the connectivity between brain regions. The connectivity of each brain region can be quantified by electroencephalography (EEG) coherence, which measures the statistical correlation between electrodes spatially separated on the scalp. Previous studies conducted a coherence analysis of all EEG electrodes covering all parts of the brain. However, in an epileptic condition, seizures occur in a specific region of the brain then spreading to other areas. Therefore, this study applies an energy-based channel selection process to determine the coherence analysis in the most active brain regions during the seizure. This paper presents a quantitative analysis of inter- and intrahemispheric coherence in epileptic EEG signals and the correlation with the channel activity to glean insights about brain area connectivity changes during epileptic seizures. The EEG signals are obtained from ten patients' data from the CHB-MIT dataset. Pair-wise electrode spectral coherence is calculated in the full band and five sub-bands of EEG signals. The channel activity level is determined by calculating the energy of each channel in all patients. The EEG coherence observation in the preictal (Cohpre) and ictal (Cohictal) conditions showed a significant decrease of Cohictal in the most active channel, especially in the lower EEG sub-bands. This finding indicates that there is a strong correlation between the decrease of mean spectral coherence and channel activity. The decrease of coherence in epileptic conditions (Cohictal <Cohpre) indicates low neuronal connectivity. There are some exceptions in some channel pairs, but a constant pattern is found in the high activity channel. This shows a strong correlation between the decrease of coherence and the channel activity. The finding in this study demonstrates that the neuronal connectivity of epileptic EEG signals is suitable to be analyzed in the more active brain regions. |
| first_indexed | 2024-12-11T16:14:55Z |
| format | Article |
| id | doaj.art-b818bcda07f0435f8f203172a9f7c2de |
| institution | Directory Open Access Journal |
| issn | 2228-7477 |
| language | English |
| last_indexed | 2024-12-11T16:14:55Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Medical Signals and Sensors |
| spelling | doaj.art-b818bcda07f0435f8f203172a9f7c2de2022-12-22T00:58:59ZengWolters Kluwer Medknow PublicationsJournal of Medical Signals and Sensors2228-74772022-01-0112214515410.4103/jmss.JMSS_63_20Quantitative analysis of inter- and intrahemispheric coherence on epileptic electroencephalography signalInung WijayantoRudy HartantoHanung Adi NugrohoWhen an epileptic seizure occurs, the neuron's activity of the brain is dynamically changed, which affects the connectivity between brain regions. The connectivity of each brain region can be quantified by electroencephalography (EEG) coherence, which measures the statistical correlation between electrodes spatially separated on the scalp. Previous studies conducted a coherence analysis of all EEG electrodes covering all parts of the brain. However, in an epileptic condition, seizures occur in a specific region of the brain then spreading to other areas. Therefore, this study applies an energy-based channel selection process to determine the coherence analysis in the most active brain regions during the seizure. This paper presents a quantitative analysis of inter- and intrahemispheric coherence in epileptic EEG signals and the correlation with the channel activity to glean insights about brain area connectivity changes during epileptic seizures. The EEG signals are obtained from ten patients' data from the CHB-MIT dataset. Pair-wise electrode spectral coherence is calculated in the full band and five sub-bands of EEG signals. The channel activity level is determined by calculating the energy of each channel in all patients. The EEG coherence observation in the preictal (Cohpre) and ictal (Cohictal) conditions showed a significant decrease of Cohictal in the most active channel, especially in the lower EEG sub-bands. This finding indicates that there is a strong correlation between the decrease of mean spectral coherence and channel activity. The decrease of coherence in epileptic conditions (Cohictal <Cohpre) indicates low neuronal connectivity. There are some exceptions in some channel pairs, but a constant pattern is found in the high activity channel. This shows a strong correlation between the decrease of coherence and the channel activity. The finding in this study demonstrates that the neuronal connectivity of epileptic EEG signals is suitable to be analyzed in the more active brain regions.http://www.jmssjournal.net/article.asp?issn=2228-7477;year=2022;volume=12;issue=2;spage=145;epage=154;aulast=Wijayantochannel activitycoherenceelectroencephalographyictalpreictalseizure |
| spellingShingle | Inung Wijayanto Rudy Hartanto Hanung Adi Nugroho Quantitative analysis of inter- and intrahemispheric coherence on epileptic electroencephalography signal Journal of Medical Signals and Sensors channel activity coherence electroencephalography ictal preictal seizure |
| title | Quantitative analysis of inter- and intrahemispheric coherence on epileptic electroencephalography signal |
| title_full | Quantitative analysis of inter- and intrahemispheric coherence on epileptic electroencephalography signal |
| title_fullStr | Quantitative analysis of inter- and intrahemispheric coherence on epileptic electroencephalography signal |
| title_full_unstemmed | Quantitative analysis of inter- and intrahemispheric coherence on epileptic electroencephalography signal |
| title_short | Quantitative analysis of inter- and intrahemispheric coherence on epileptic electroencephalography signal |
| title_sort | quantitative analysis of inter and intrahemispheric coherence on epileptic electroencephalography signal |
| topic | channel activity coherence electroencephalography ictal preictal seizure |
| url | http://www.jmssjournal.net/article.asp?issn=2228-7477;year=2022;volume=12;issue=2;spage=145;epage=154;aulast=Wijayanto |
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