Cancer Predisposition Genes in Cancer-Free Families

Cancer Predisposition Genes in Cancer-Free Families

Familial clustering, twin concordance, and identification of high- and low-penetrance cancer predisposition variants support the idea that there are families that are at a high to moderate excess risk of cancer. To what extent there may be families that are protected from cancer is unknown. We wante...

Full description

Bibliographic Details
Main Authors: Guoqiao Zheng, Calogerina Catalano, Obul Reddy Bandapalli, Nagarajan Paramasivam, Subhayan Chattopadhyay, Matthias Schlesner, Rolf Sijmons, Akseli Hemminki, Dagmara Dymerska, Jan Lubinski, Kari Hemminki, Asta Försti
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
predisposing genes
high-risk genes
polygenic risk
random environment
Online Access:https://www.mdpi.com/2072-6694/12/10/2770

Similar Items

Similar Items