cGAS Regulates the Radioresistance of Human Head and Neck Squamous Cell Carcinoma Cells

cGAS Regulates the Radioresistance of Human Head and Neck Squamous Cell Carcinoma Cells

Cyclic GMP-AMP synthase (cGAS) plays an important role in biological responses to pathogens. The activation of the cGAS pathway in immune cells is known to induce antitumor effects, but the role of cGAS in cancer cells remains poorly understood. In silico analysis using public databases suggested th...

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Bibliographic Details
Main Authors: Taichi Nyui, Hironori Yoshino, Tetsuya Nunota, Yoshiaki Sato, Eichi Tsuruga
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
cyclic GMP-AMP synthase
head and neck squamous cell carcinoma
radiosensitivity
apoptosis
mitotic catastrophe
cellular senescence
Online Access:https://www.mdpi.com/2073-4409/11/9/1434

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