In Silico Analyses and Cytotoxicity Study of Asiaticoside and Asiatic Acid from Malaysian Plant as Potential mTOR Inhibitors

In Silico Analyses and Cytotoxicity Study of Asiaticoside and Asiatic Acid from Malaysian Plant as Potential mTOR Inhibitors

Natural products remain a popular alternative treatment for many ailments in various countries. This study aimed to screen for potential mammalian target of rapamycin (mTOR) inhibitors from Malaysian natural substance, using the Natural Product Discovery database, and to determine the IC<sub>5...

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Bibliographic Details
Main Authors: Ninie Nadia Zulkipli, Rahimah Zakaria, Idris Long, Siti Fadilah Abdullah, Erma Fatiha Muhammad, Habibah A. Wahab, Teguh Haryo Sasongko
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
mammalian target of rapamycin (mTOR)
molecular docking
everolimus
asiaticoside
asiatic acid
IC<sub>50</sub>
Online Access:https://www.mdpi.com/1420-3049/25/17/3991

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