Category verbal fluency performance may be impaired in amnestic mild cognitive impairment
Abstract To study category verbal fluency (VF) for animals in patients with amnestic mild cognitive impairment (aMCI), mild Alzheimer disease (AD) and normal controls. Method: Fifteen mild AD, 15 aMCI, and 15 normal control subjects were included. Diagnosis of AD was based on DSM-IV and NINCDS-ADRD...
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| Format: | Article |
| Language: | English |
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Associação Neurologia Cognitiva e do Comportamento
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| Series: | Dementia & Neuropsychologia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642007000200161&lng=en&tlng=en |
| _version_ | 1818149554108760064 |
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| author | Márcio Luiz Figueredo Balthazar Fernando Cendes Benito Pereira Damasceno |
| author_facet | Márcio Luiz Figueredo Balthazar Fernando Cendes Benito Pereira Damasceno |
| author_sort | Márcio Luiz Figueredo Balthazar |
| collection | DOAJ |
| description | Abstract To study category verbal fluency (VF) for animals in patients with amnestic mild cognitive impairment (aMCI), mild Alzheimer disease (AD) and normal controls. Method: Fifteen mild AD, 15 aMCI, and 15 normal control subjects were included. Diagnosis of AD was based on DSM-IV and NINCDS-ADRDA criteria, while aMCI was based on the criteria of the International Working Group on Mild Cognitive Impairment, using CDR 0.5 for aMCI and CDR 1 for mild AD. All subjects underwent testing of category VF for animals, lexical semantic function (Boston Naming-BNT, CAMCOG Similarities item), WAIS-R forward and backward digit span, Rey Auditory Verbal Learning (RAVLT), Mini-Mental Status Examination (MMSE), and other task relevant functions such as visual perception, attention, and mood state (with Cornell Scale for Depression in Dementia). Data analysis used ANOVA and a post-hoc Tukey test for intergroup comparisons, and Pearson's coefficient for correlations of memory and FV tests with other task relevant functions (statistical significance level was p<0.05). Results: aMCI patients had lower performance than controls on category VF for animals and on the backward digit span subtest of WAIS-R but higher scores compared with mild AD patients. Mild AD patients scored significantly worse than aMCI and controls across all tests. Conclusion: aMCI patients may have poor performance in some non-memory tests, specifically category VF for animals in our study, where this could be attributable to the influence of working memory. |
| first_indexed | 2024-12-11T13:08:53Z |
| format | Article |
| id | doaj.art-b8237545bde142b88344ae5c47f43bce |
| institution | Directory Open Access Journal |
| issn | 1980-5764 |
| language | English |
| last_indexed | 2024-12-11T13:08:53Z |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| record_format | Article |
| series | Dementia & Neuropsychologia |
| spelling | doaj.art-b8237545bde142b88344ae5c47f43bce2022-12-22T01:06:15ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-57641216116510.1590/s1980-57642008dn10200008S1980-57642007000200161Category verbal fluency performance may be impaired in amnestic mild cognitive impairmentMárcio Luiz Figueredo BalthazarFernando CendesBenito Pereira DamascenoAbstract To study category verbal fluency (VF) for animals in patients with amnestic mild cognitive impairment (aMCI), mild Alzheimer disease (AD) and normal controls. Method: Fifteen mild AD, 15 aMCI, and 15 normal control subjects were included. Diagnosis of AD was based on DSM-IV and NINCDS-ADRDA criteria, while aMCI was based on the criteria of the International Working Group on Mild Cognitive Impairment, using CDR 0.5 for aMCI and CDR 1 for mild AD. All subjects underwent testing of category VF for animals, lexical semantic function (Boston Naming-BNT, CAMCOG Similarities item), WAIS-R forward and backward digit span, Rey Auditory Verbal Learning (RAVLT), Mini-Mental Status Examination (MMSE), and other task relevant functions such as visual perception, attention, and mood state (with Cornell Scale for Depression in Dementia). Data analysis used ANOVA and a post-hoc Tukey test for intergroup comparisons, and Pearson's coefficient for correlations of memory and FV tests with other task relevant functions (statistical significance level was p<0.05). Results: aMCI patients had lower performance than controls on category VF for animals and on the backward digit span subtest of WAIS-R but higher scores compared with mild AD patients. Mild AD patients scored significantly worse than aMCI and controls across all tests. Conclusion: aMCI patients may have poor performance in some non-memory tests, specifically category VF for animals in our study, where this could be attributable to the influence of working memory.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642007000200161&lng=en&tlng=enfluência verbalcomprometimento cognitivo levedoença de Alzheimertestes neuropsicológicos. |
| spellingShingle | Márcio Luiz Figueredo Balthazar Fernando Cendes Benito Pereira Damasceno Category verbal fluency performance may be impaired in amnestic mild cognitive impairment Dementia & Neuropsychologia fluência verbal comprometimento cognitivo leve doença de Alzheimer testes neuropsicológicos. |
| title | Category verbal fluency performance may be impaired in amnestic mild cognitive impairment |
| title_full | Category verbal fluency performance may be impaired in amnestic mild cognitive impairment |
| title_fullStr | Category verbal fluency performance may be impaired in amnestic mild cognitive impairment |
| title_full_unstemmed | Category verbal fluency performance may be impaired in amnestic mild cognitive impairment |
| title_short | Category verbal fluency performance may be impaired in amnestic mild cognitive impairment |
| title_sort | category verbal fluency performance may be impaired in amnestic mild cognitive impairment |
| topic | fluência verbal comprometimento cognitivo leve doença de Alzheimer testes neuropsicológicos. |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642007000200161&lng=en&tlng=en |
| work_keys_str_mv | AT marcioluizfigueredobalthazar categoryverbalfluencyperformancemaybeimpairedinamnesticmildcognitiveimpairment AT fernandocendes categoryverbalfluencyperformancemaybeimpairedinamnesticmildcognitiveimpairment AT benitopereiradamasceno categoryverbalfluencyperformancemaybeimpairedinamnesticmildcognitiveimpairment |