Supplement Use and Increased Risks of Cancer: Unveiling the Other Side of the Coin

There is a rising trend in the consumption of dietary supplements, especially among adults, with the purpose of improving health. While marketing campaigns tout the potential health benefits of using dietary supplements, it is critical to evaluate the potential harmful effects associated with these...

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Main Authors: Parnian Jabbari, Omid Yazdanpanah, David J. Benjamin, Arash Rezazadeh Kalebasty
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/16/5/880
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author Parnian Jabbari
Omid Yazdanpanah
David J. Benjamin
Arash Rezazadeh Kalebasty
author_facet Parnian Jabbari
Omid Yazdanpanah
David J. Benjamin
Arash Rezazadeh Kalebasty
author_sort Parnian Jabbari
collection DOAJ
description There is a rising trend in the consumption of dietary supplements, especially among adults, with the purpose of improving health. While marketing campaigns tout the potential health benefits of using dietary supplements, it is critical to evaluate the potential harmful effects associated with these supplements as well. The majority of the scarce research on the potential harmful effects of vitamins focuses on the acute or chronic toxicities associated with the use of dietary supplements. Quality research is still required to further investigate the risks of long-term use of dietary supplements, especially the risk of developing cancers. The present review concentrates on studies that have investigated the association between the risk of developing cancers and associated mortality with the risk of dietary supplements. Such an association has been reported for several vitamins, minerals, and other dietary supplements. Even though several of these studies come with their own shortcomings and critics, they must draw attention to further investigate long-term adverse effects of dietary supplements and advise consumers and healthcare providers to ponder the extensive use of dietary supplements.
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spelling doaj.art-b824ae960d4d42e6a6a4721d05eeb08c2024-03-12T16:40:42ZengMDPI AGCancers2072-66942024-02-0116588010.3390/cancers16050880Supplement Use and Increased Risks of Cancer: Unveiling the Other Side of the CoinParnian Jabbari0Omid Yazdanpanah1David J. Benjamin2Arash Rezazadeh Kalebasty3Department of Cell, Molecular and Systems Biology, University of California, Riverside, CA 92521, USADivision of Hematology and Oncology, Department of Medicine, University of California Irvine Medical Center, Orange, CA 92868, USAHoag Family Cancer Institute, Newport Beach, CA 92663, USADivision of Hematology and Oncology, Department of Medicine, University of California Irvine Medical Center, Orange, CA 92868, USAThere is a rising trend in the consumption of dietary supplements, especially among adults, with the purpose of improving health. While marketing campaigns tout the potential health benefits of using dietary supplements, it is critical to evaluate the potential harmful effects associated with these supplements as well. The majority of the scarce research on the potential harmful effects of vitamins focuses on the acute or chronic toxicities associated with the use of dietary supplements. Quality research is still required to further investigate the risks of long-term use of dietary supplements, especially the risk of developing cancers. The present review concentrates on studies that have investigated the association between the risk of developing cancers and associated mortality with the risk of dietary supplements. Such an association has been reported for several vitamins, minerals, and other dietary supplements. Even though several of these studies come with their own shortcomings and critics, they must draw attention to further investigate long-term adverse effects of dietary supplements and advise consumers and healthcare providers to ponder the extensive use of dietary supplements.https://www.mdpi.com/2072-6694/16/5/880vitaminsupplementcancer riskprostate cancer
spellingShingle Parnian Jabbari
Omid Yazdanpanah
David J. Benjamin
Arash Rezazadeh Kalebasty
Supplement Use and Increased Risks of Cancer: Unveiling the Other Side of the Coin
Cancers
vitamin
supplement
cancer risk
prostate cancer
title Supplement Use and Increased Risks of Cancer: Unveiling the Other Side of the Coin
title_full Supplement Use and Increased Risks of Cancer: Unveiling the Other Side of the Coin
title_fullStr Supplement Use and Increased Risks of Cancer: Unveiling the Other Side of the Coin
title_full_unstemmed Supplement Use and Increased Risks of Cancer: Unveiling the Other Side of the Coin
title_short Supplement Use and Increased Risks of Cancer: Unveiling the Other Side of the Coin
title_sort supplement use and increased risks of cancer unveiling the other side of the coin
topic vitamin
supplement
cancer risk
prostate cancer
url https://www.mdpi.com/2072-6694/16/5/880
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