Transcarotid versus transfemoral access for cerebrovascular intervention: protocol for a systematic review and meta-analysis
Introduction Cerebrovascular intervention is an excellent option to treat cerebrovascular diseases. Interventional access is a prerequisite and a foundation for cerebrovascular intervention, which is crucial to the success of an intervention. Although transfemoral arterial access (TFA) has become a...
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BMJ Publishing Group
2023-06-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/13/6/e071820.full |
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| author | Yan Ma Tao Wang Yanfei Chen Jichang Luo Renjie Yang Wanying Liao Dong Lei Zixuan Xing Wenlong Xu Haozhi Gong |
| author_facet | Yan Ma Tao Wang Yanfei Chen Jichang Luo Renjie Yang Wanying Liao Dong Lei Zixuan Xing Wenlong Xu Haozhi Gong |
| author_sort | Yan Ma |
| collection | DOAJ |
| description | Introduction Cerebrovascular intervention is an excellent option to treat cerebrovascular diseases. Interventional access is a prerequisite and a foundation for cerebrovascular intervention, which is crucial to the success of an intervention. Although transfemoral arterial access (TFA) has become a popular and acceptable method of access for cerebrovascular angiography and intervention in clinical practice, it has some drawbacks that limit the usage in cerebrovascular interventions. Therefore, transcarotid arterial access (TCA) has been developed in cerebrovascular interventions. We aim to conduct a systematic review to compare the safety and efficacy of TCA with TFA for cerebrovascular intervention.Methods and analysis In this protocol, Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols were followed. PubMed, Embase, Web of Science and the Cochrane Central Register of Controlled Trials will be searched mainly from 1 January 2004, to the formal search date. Additionally, reference lists and clinical trial registries will be searched. We will include clinical trials with more than 30 participants, which reported the endpoints of stroke, death and myocardial infarction. Two investigators will independently select studies, extract data and assess bias risk. A standardised mean difference with 95% CI will be presented for continuous data, and a risk ratio with 95% CI will be presented for dichotomous data. On inclusion of sufficient studies, subgroup analysis and sensitivity analysis will be conducted. The funnel plot and Egger’s test will be used to assess publication bias.Ethics and dissemination As only published sources will be used in this review, ethical approval is not required. We will publish the results in a peer-reviewed journal.PROSPERO registration number CRD42022316468. |
| first_indexed | 2024-03-11T19:43:46Z |
| format | Article |
| id | doaj.art-b824fff0f45e4180bb379e41ba7d7e08 |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-03-11T19:43:46Z |
| publishDate | 2023-06-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-b824fff0f45e4180bb379e41ba7d7e082023-10-06T05:40:07ZengBMJ Publishing GroupBMJ Open2044-60552023-06-0113610.1136/bmjopen-2023-071820Transcarotid versus transfemoral access for cerebrovascular intervention: protocol for a systematic review and meta-analysisYan Ma0Tao Wang1Yanfei Chen2Jichang Luo3Renjie Yang4Wanying Liao5Dong Lei6Zixuan Xing7Wenlong Xu8Haozhi Gong9Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing, ChinaDepartment of Neurosurgery, Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, National Center for Neurological Disorders, Beijing, ChinaChina International Neuroscience Institute (China-INI), Beijing, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, Beijing, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, Beijing, ChinaPeking Union Medical College and Chinese Academy of Medical Sciences, Beijing, ChinaDepartment of Neurology, Tianjin Baodi Hospital, Tianjin, ChinaHealth Science Center, Xi`an Jiaotong University, Xi`an, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, Beijing, ChinaIntroduction Cerebrovascular intervention is an excellent option to treat cerebrovascular diseases. Interventional access is a prerequisite and a foundation for cerebrovascular intervention, which is crucial to the success of an intervention. Although transfemoral arterial access (TFA) has become a popular and acceptable method of access for cerebrovascular angiography and intervention in clinical practice, it has some drawbacks that limit the usage in cerebrovascular interventions. Therefore, transcarotid arterial access (TCA) has been developed in cerebrovascular interventions. We aim to conduct a systematic review to compare the safety and efficacy of TCA with TFA for cerebrovascular intervention.Methods and analysis In this protocol, Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols were followed. PubMed, Embase, Web of Science and the Cochrane Central Register of Controlled Trials will be searched mainly from 1 January 2004, to the formal search date. Additionally, reference lists and clinical trial registries will be searched. We will include clinical trials with more than 30 participants, which reported the endpoints of stroke, death and myocardial infarction. Two investigators will independently select studies, extract data and assess bias risk. A standardised mean difference with 95% CI will be presented for continuous data, and a risk ratio with 95% CI will be presented for dichotomous data. On inclusion of sufficient studies, subgroup analysis and sensitivity analysis will be conducted. The funnel plot and Egger’s test will be used to assess publication bias.Ethics and dissemination As only published sources will be used in this review, ethical approval is not required. We will publish the results in a peer-reviewed journal.PROSPERO registration number CRD42022316468.https://bmjopen.bmj.com/content/13/6/e071820.full |
| spellingShingle | Yan Ma Tao Wang Yanfei Chen Jichang Luo Renjie Yang Wanying Liao Dong Lei Zixuan Xing Wenlong Xu Haozhi Gong Transcarotid versus transfemoral access for cerebrovascular intervention: protocol for a systematic review and meta-analysis BMJ Open |
| title | Transcarotid versus transfemoral access for cerebrovascular intervention: protocol for a systematic review and meta-analysis |
| title_full | Transcarotid versus transfemoral access for cerebrovascular intervention: protocol for a systematic review and meta-analysis |
| title_fullStr | Transcarotid versus transfemoral access for cerebrovascular intervention: protocol for a systematic review and meta-analysis |
| title_full_unstemmed | Transcarotid versus transfemoral access for cerebrovascular intervention: protocol for a systematic review and meta-analysis |
| title_short | Transcarotid versus transfemoral access for cerebrovascular intervention: protocol for a systematic review and meta-analysis |
| title_sort | transcarotid versus transfemoral access for cerebrovascular intervention protocol for a systematic review and meta analysis |
| url | https://bmjopen.bmj.com/content/13/6/e071820.full |
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