Keratoplasty rejection after messenger RNA vaccine (BNT162b2) for COVID-19

This report shows a case of corneal transplant rejection after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), short after receiving the BNT162b2 vaccine, in a patient who had undergone keratoplasty more than 20 years ago, with no previous episodes of rejection and...

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Main Authors: Maria Eduarda Andrade e Andrade, Juliane Cardoso Rodrigues, Elvio Ferreira Junior, Mario Henrique Camargos de Lima
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=8;spage=3134;epage=3136;aulast=Eduarda
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author Maria Eduarda Andrade e Andrade
Juliane Cardoso Rodrigues
Elvio Ferreira Junior
Mario Henrique Camargos de Lima
author_facet Maria Eduarda Andrade e Andrade
Juliane Cardoso Rodrigues
Elvio Ferreira Junior
Mario Henrique Camargos de Lima
author_sort Maria Eduarda Andrade e Andrade
collection DOAJ
description This report shows a case of corneal transplant rejection after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), short after receiving the BNT162b2 vaccine, in a patient who had undergone keratoplasty more than 20 years ago, with no previous episodes of rejection and no other factor that could lead to the findings on his examinations. After treatment with high doses of topic, oral, and sub-conjunctival corticoids, the patient had a favorable therapeutic response. The signs of corneal transplant rejection must be oriented to the patients and the causing factors actively searched by ophthalmologists so that treatment is rapidly initiated and sequels are avoided. This report raises the question if these events are correlated and whether the patient should receive the second dose of the vaccine against SARS-CoV-2 or not.
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spelling doaj.art-b8258f2d8dee4ce9b3cd1e05beb338322022-12-22T04:01:34ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892022-01-017083134313610.4103/ijo.IJO_1021_22Keratoplasty rejection after messenger RNA vaccine (BNT162b2) for COVID-19Maria Eduarda Andrade e AndradeJuliane Cardoso RodriguesElvio Ferreira JuniorMario Henrique Camargos de LimaThis report shows a case of corneal transplant rejection after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), short after receiving the BNT162b2 vaccine, in a patient who had undergone keratoplasty more than 20 years ago, with no previous episodes of rejection and no other factor that could lead to the findings on his examinations. After treatment with high doses of topic, oral, and sub-conjunctival corticoids, the patient had a favorable therapeutic response. The signs of corneal transplant rejection must be oriented to the patients and the causing factors actively searched by ophthalmologists so that treatment is rapidly initiated and sequels are avoided. This report raises the question if these events are correlated and whether the patient should receive the second dose of the vaccine against SARS-CoV-2 or not.http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=8;spage=3134;epage=3136;aulast=Eduardabnt162b2 vaccinecoronaviruskeratoplastypenetratingvaccine
spellingShingle Maria Eduarda Andrade e Andrade
Juliane Cardoso Rodrigues
Elvio Ferreira Junior
Mario Henrique Camargos de Lima
Keratoplasty rejection after messenger RNA vaccine (BNT162b2) for COVID-19
Indian Journal of Ophthalmology
bnt162b2 vaccine
coronavirus
keratoplasty
penetrating
vaccine
title Keratoplasty rejection after messenger RNA vaccine (BNT162b2) for COVID-19
title_full Keratoplasty rejection after messenger RNA vaccine (BNT162b2) for COVID-19
title_fullStr Keratoplasty rejection after messenger RNA vaccine (BNT162b2) for COVID-19
title_full_unstemmed Keratoplasty rejection after messenger RNA vaccine (BNT162b2) for COVID-19
title_short Keratoplasty rejection after messenger RNA vaccine (BNT162b2) for COVID-19
title_sort keratoplasty rejection after messenger rna vaccine bnt162b2 for covid 19
topic bnt162b2 vaccine
coronavirus
keratoplasty
penetrating
vaccine
url http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=8;spage=3134;epage=3136;aulast=Eduarda
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