Propolis Controlled Delivery Systems for Oral Therapeutics in Dental Medicine: A Systematic Review
This systematic review synthesizes the existing evidence in the literature regarding the association of propolis with controlled delivery systems (DDSs) and its potential therapeutic action in dental medicine. Two independent reviewers performed a literature search up to 1 June 2023 in five database...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Dentistry Journal |
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| Online Access: | https://www.mdpi.com/2304-6767/11/7/162 |
| _version_ | 1797589682346786816 |
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| author | Andressa da Silva Barboza Juliana Silva Ribeiro de Andrade Monika Lamas Ferreira Carla Lucía David Peña Juliê Silveira da Costa André Ricardo Fajardo Rafael Guerra Lund |
| author_facet | Andressa da Silva Barboza Juliana Silva Ribeiro de Andrade Monika Lamas Ferreira Carla Lucía David Peña Juliê Silveira da Costa André Ricardo Fajardo Rafael Guerra Lund |
| author_sort | Andressa da Silva Barboza |
| collection | DOAJ |
| description | This systematic review synthesizes the existing evidence in the literature regarding the association of propolis with controlled delivery systems (DDSs) and its potential therapeutic action in dental medicine. Two independent reviewers performed a literature search up to 1 June 2023 in five databases: PubMed/Medline, Web of Science, Cochrane Library, Scopus, and Embase, to identify the eligible studies. Clinical, in situ, and in vitro studies that investigated the incorporation of propolis as the main agent in DDSs for dental medicine were included in this study. Review articles, clinical cases, theses, dissertations, conference abstracts, and studies that had no application in dentistry were excluded. A total of 2019 records were initially identified. After carefully examining 21 full-text articles, 12 in vitro studies, 4 clinical, 1 animal model, and 3 in vivo and in vitro studies were included (n = 21). Relevant data were extracted from the included studies and analyzed qualitatively. The use of propolis has been reported in cariology, endodontics, periodontics, stomatology, and dental implants. Propolis has shown non-cytotoxic, osteoinductive, antimicrobial, and anti-inflammatory properties. Moreover, propolis can be released from DDS for prolonged periods, presenting biocompatibility, safety, and potential advantage for applications in dental medicine. |
| first_indexed | 2024-03-11T01:10:01Z |
| format | Article |
| id | doaj.art-b829d74fe0cc416892f801fc93103f3b |
| institution | Directory Open Access Journal |
| issn | 2304-6767 |
| language | English |
| last_indexed | 2024-03-11T01:10:01Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Dentistry Journal |
| spelling | doaj.art-b829d74fe0cc416892f801fc93103f3b2023-11-18T18:56:38ZengMDPI AGDentistry Journal2304-67672023-06-0111716210.3390/dj11070162Propolis Controlled Delivery Systems for Oral Therapeutics in Dental Medicine: A Systematic ReviewAndressa da Silva Barboza0Juliana Silva Ribeiro de Andrade1Monika Lamas Ferreira2Carla Lucía David Peña3Juliê Silveira da Costa4André Ricardo Fajardo5Rafael Guerra Lund6Graduate Program in Dentistry, Pelotas Dental School, Federal University of Pelotas, Gonçalves Chaves Street, 457/Rm 702-3, Downtown Pelotas, Pelotas 96015-560, RS, BrazilGraduate Program in Dentistry, Pelotas Dental School, Federal University of Pelotas, Gonçalves Chaves Street, 457/Rm 702-3, Downtown Pelotas, Pelotas 96015-560, RS, BrazilGraduate Program in Dentistry, Pelotas Dental School, Federal University of Pelotas, Gonçalves Chaves Street, 457/Rm 702-3, Downtown Pelotas, Pelotas 96015-560, RS, BrazilGraduate Program in Dentistry, Pelotas Dental School, Federal University of Pelotas, Gonçalves Chaves Street, 457/Rm 702-3, Downtown Pelotas, Pelotas 96015-560, RS, BrazilLaboratory of Technology and Development of Composites and Polymeric Materials (LaCoPol), Center for Chemical, Pharmaceutical and Food Sciences, Federal University of Pelotas, UFPel, Campus Capão do Leão, Pelotas 96010-900, RS, BrazilLaboratory of Technology and Development of Composites and Polymeric Materials (LaCoPol), Center for Chemical, Pharmaceutical and Food Sciences, Federal University of Pelotas, UFPel, Campus Capão do Leão, Pelotas 96010-900, RS, BrazilGraduate Program in Dentistry, Pelotas Dental School, Federal University of Pelotas, Gonçalves Chaves Street, 457/Rm 702-3, Downtown Pelotas, Pelotas 96015-560, RS, BrazilThis systematic review synthesizes the existing evidence in the literature regarding the association of propolis with controlled delivery systems (DDSs) and its potential therapeutic action in dental medicine. Two independent reviewers performed a literature search up to 1 June 2023 in five databases: PubMed/Medline, Web of Science, Cochrane Library, Scopus, and Embase, to identify the eligible studies. Clinical, in situ, and in vitro studies that investigated the incorporation of propolis as the main agent in DDSs for dental medicine were included in this study. Review articles, clinical cases, theses, dissertations, conference abstracts, and studies that had no application in dentistry were excluded. A total of 2019 records were initially identified. After carefully examining 21 full-text articles, 12 in vitro studies, 4 clinical, 1 animal model, and 3 in vivo and in vitro studies were included (n = 21). Relevant data were extracted from the included studies and analyzed qualitatively. The use of propolis has been reported in cariology, endodontics, periodontics, stomatology, and dental implants. Propolis has shown non-cytotoxic, osteoinductive, antimicrobial, and anti-inflammatory properties. Moreover, propolis can be released from DDS for prolonged periods, presenting biocompatibility, safety, and potential advantage for applications in dental medicine.https://www.mdpi.com/2304-6767/11/7/162propolisoral bone regenerationdrug deliveryguided tissue regenerationtissue engineeringsystematic review |
| spellingShingle | Andressa da Silva Barboza Juliana Silva Ribeiro de Andrade Monika Lamas Ferreira Carla Lucía David Peña Juliê Silveira da Costa André Ricardo Fajardo Rafael Guerra Lund Propolis Controlled Delivery Systems for Oral Therapeutics in Dental Medicine: A Systematic Review Dentistry Journal propolis oral bone regeneration drug delivery guided tissue regeneration tissue engineering systematic review |
| title | Propolis Controlled Delivery Systems for Oral Therapeutics in Dental Medicine: A Systematic Review |
| title_full | Propolis Controlled Delivery Systems for Oral Therapeutics in Dental Medicine: A Systematic Review |
| title_fullStr | Propolis Controlled Delivery Systems for Oral Therapeutics in Dental Medicine: A Systematic Review |
| title_full_unstemmed | Propolis Controlled Delivery Systems for Oral Therapeutics in Dental Medicine: A Systematic Review |
| title_short | Propolis Controlled Delivery Systems for Oral Therapeutics in Dental Medicine: A Systematic Review |
| title_sort | propolis controlled delivery systems for oral therapeutics in dental medicine a systematic review |
| topic | propolis oral bone regeneration drug delivery guided tissue regeneration tissue engineering systematic review |
| url | https://www.mdpi.com/2304-6767/11/7/162 |
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