Clozapine generates obsessive compulsive disorder-like behavior in mice

Abstract Clozapine is thought to induce obsessive compulsive symptoms (OCS) in schizophrenic patients. However, because OCS are often comorbid with schizophrenia regardless of clozapine treatment, it remains unclear whether clozapine can generate OCS de novo. Thus, it has been difficult to establish...

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Bibliographic Details
Main Authors: Shinwon Kang, Hyun Jong Noh, Soo Hyeon Bae, Yong-Seok Kim, Hogun Lew, Jisoo Lim, Se Joo Kim, Kyung Sue Hong, Jong-Cheol Rah, Chul Hoon Kim
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Molecular Brain
Online Access:http://link.springer.com/article/10.1186/s13041-020-00621-5