Solving the Reach Problem: A Review of Present and Future Approaches for Addressing Ventricular Arrhythmias Arising from Deep Substrate
Ventricular tachycardia (VT) is a significant cause of morbidity and mortality in patients with ischaemic and non-ischaemic cardiomyopathies. In most patients, the primary strategy of VT catheter ablation is based on the identification of critical components of reentry circuits and modification of a...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Radcliffe Medical Media
2023-01-01
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| Series: | Arrhythmia & Electrophysiology Review |
| Online Access: | https://www.aerjournal.com/articles/solving-reach-problem-review-present-and-future-approaches-addressing-ventricular#ArticleTextTab |
| _version_ | 1797823238066143232 |
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| author | Venkatesh Ravi Jeffrey Winterfield Jackson Liang Timothy Larsen Cicely Dye David Sanders Jamario Skeete Josh Payne Richard G Trohman Tolga Aksu Parikshit S Sharma Henry D Huang |
| author_facet | Venkatesh Ravi Jeffrey Winterfield Jackson Liang Timothy Larsen Cicely Dye David Sanders Jamario Skeete Josh Payne Richard G Trohman Tolga Aksu Parikshit S Sharma Henry D Huang |
| author_sort | Venkatesh Ravi |
| collection | DOAJ |
| description | Ventricular tachycardia (VT) is a significant cause of morbidity and mortality in patients with ischaemic and non-ischaemic cardiomyopathies. In most patients, the primary strategy of VT catheter ablation is based on the identification of critical components of reentry circuits and modification of abnormal substrate which can initiate reentry. Despite technological advancements in catheter design and improved ability to localise abnormal substrates, putative circuits and site of origins of ventricular arrhythmias (VAs), current technologies remain inadequate and durable success may be elusive when the critical substrate is deep or near to critical structures that are at risk of collateral damage. In this article, we review the available and potential future non-surgical investigational approaches for treatment of VAs and discuss the viability of these modalities. |
| first_indexed | 2024-03-13T10:21:04Z |
| format | Article |
| id | doaj.art-b82d2cdde3a74ff19d14a10e12c2712a |
| institution | Directory Open Access Journal |
| issn | 2050-3377 |
| language | English |
| last_indexed | 2024-03-13T10:21:04Z |
| publishDate | 2023-01-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | Arrhythmia & Electrophysiology Review |
| spelling | doaj.art-b82d2cdde3a74ff19d14a10e12c2712a2023-05-20T16:04:00ZengRadcliffe Medical MediaArrhythmia & Electrophysiology Review2050-33772023-01-0110.15420/aer.2022.28Solving the Reach Problem: A Review of Present and Future Approaches for Addressing Ventricular Arrhythmias Arising from Deep SubstrateVenkatesh RaviJeffrey WinterfieldJackson LiangTimothy LarsenCicely DyeDavid SandersJamario SkeeteJosh PayneRichard G TrohmanTolga AksuParikshit S SharmaHenry D HuangVentricular tachycardia (VT) is a significant cause of morbidity and mortality in patients with ischaemic and non-ischaemic cardiomyopathies. In most patients, the primary strategy of VT catheter ablation is based on the identification of critical components of reentry circuits and modification of abnormal substrate which can initiate reentry. Despite technological advancements in catheter design and improved ability to localise abnormal substrates, putative circuits and site of origins of ventricular arrhythmias (VAs), current technologies remain inadequate and durable success may be elusive when the critical substrate is deep or near to critical structures that are at risk of collateral damage. In this article, we review the available and potential future non-surgical investigational approaches for treatment of VAs and discuss the viability of these modalities.https://www.aerjournal.com/articles/solving-reach-problem-review-present-and-future-approaches-addressing-ventricular#ArticleTextTab |
| spellingShingle | Venkatesh Ravi Jeffrey Winterfield Jackson Liang Timothy Larsen Cicely Dye David Sanders Jamario Skeete Josh Payne Richard G Trohman Tolga Aksu Parikshit S Sharma Henry D Huang Solving the Reach Problem: A Review of Present and Future Approaches for Addressing Ventricular Arrhythmias Arising from Deep Substrate Arrhythmia & Electrophysiology Review |
| title | Solving the Reach Problem: A Review of Present and Future Approaches for Addressing Ventricular Arrhythmias Arising from Deep Substrate |
| title_full | Solving the Reach Problem: A Review of Present and Future Approaches for Addressing Ventricular Arrhythmias Arising from Deep Substrate |
| title_fullStr | Solving the Reach Problem: A Review of Present and Future Approaches for Addressing Ventricular Arrhythmias Arising from Deep Substrate |
| title_full_unstemmed | Solving the Reach Problem: A Review of Present and Future Approaches for Addressing Ventricular Arrhythmias Arising from Deep Substrate |
| title_short | Solving the Reach Problem: A Review of Present and Future Approaches for Addressing Ventricular Arrhythmias Arising from Deep Substrate |
| title_sort | solving the reach problem a review of present and future approaches for addressing ventricular arrhythmias arising from deep substrate |
| url | https://www.aerjournal.com/articles/solving-reach-problem-review-present-and-future-approaches-addressing-ventricular#ArticleTextTab |
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