Moderate hypofractionation in prostate cancer: experience from Regional Hospital ISSSTE, Morelos
Purpose: To describe the institutional experience of treatment with volumetric modulated arc therapy (VMAT) in prostate cancer in the Mexican population of the Regional Hospital “Centenario de la Revolución Mexicana”, ISSSTE, Morelos. Methods: A retrospective study of patients with prostate cancer t...
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| Format: | Article |
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Permanyer
2023-01-01
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| Series: | Revista Médica del Hospital General de México |
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| Online Access: | https://www.hospitalgeneral.com/frame_esp.php?id=153 |
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| author | Felipe de J. Tallabs-Villafaña Oscar S. Salinas-Rosas María F. Rivera-Valaguez Palemón Gutiérrez-Balderas Verónica Andrade-Almaraz |
| author_facet | Felipe de J. Tallabs-Villafaña Oscar S. Salinas-Rosas María F. Rivera-Valaguez Palemón Gutiérrez-Balderas Verónica Andrade-Almaraz |
| author_sort | Felipe de J. Tallabs-Villafaña |
| collection | DOAJ |
| description | Purpose: To describe the institutional experience of treatment with volumetric modulated arc therapy (VMAT) in prostate cancer in the Mexican population of the Regional Hospital “Centenario de la Revolución Mexicana”, ISSSTE, Morelos. Methods: A retrospective study of patients with prostate cancer treated with radiotherapy with moderate hypofractionation at doses of 70.2Gy in 26 fractions was performed, between January 2017 and January 2021. Results: 55 patients were included in the analysis, with a median follow-up of 20.7 months, biochemical control was 100%. Acute gastrointestinal toxicity grade 1 or less occurred in 87.3% of patients, grade 2: 9.1% y grade 3 in 3.6%; acute genitourinary toxicity grade 1 or less in 90.9%, grade 2: 7.3% and grade 3: 1.8%. Regarding chronic gastrointestinal toxicity grade 1 or less, it was 95.3%, grade 2: 4.8%, There have been no grade 3 or higher cases, chronic genitourinary toxicity grade 1 or less 90.5%, grade 2: 7.1%, grade 3: 2.4%. Conclusions: Moderate hypofractionation in prostate cancer in the Mexican population presents excellent biochemical control and an adequate toxicity profile.
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| first_indexed | 2024-04-10T09:35:43Z |
| format | Article |
| id | doaj.art-b82d4b45a6f4492ebfd5f21990da3c6f |
| institution | Directory Open Access Journal |
| issn | 0185-1063 |
| language | English |
| last_indexed | 2024-04-10T09:35:43Z |
| publishDate | 2023-01-01 |
| publisher | Permanyer |
| record_format | Article |
| series | Revista Médica del Hospital General de México |
| spelling | doaj.art-b82d4b45a6f4492ebfd5f21990da3c6f2023-02-17T19:48:02ZengPermanyerRevista Médica del Hospital General de México0185-10632023-01-0186110.24875/HGMX.22000059Moderate hypofractionation in prostate cancer: experience from Regional Hospital ISSSTE, MorelosFelipe de J. Tallabs-Villafaña0Oscar S. Salinas-Rosas1María F. Rivera-Valaguez2Palemón Gutiérrez-Balderas3Verónica Andrade-Almaraz4Radiotherapy Service, Hospital de Alta Especialidad “Centenario de la Revolución Mexicana”, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Emiliano Zapata, Mor., MexicoCoordination of Teaching and Research. Hospital de Alta Especialidad “Centenario de la Revolución Mexicana”, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Emiliano Zapata, Mor., MexicoCoordination of Teaching and Research. Hospital de Alta Especialidad “Centenario de la Revolución Mexicana”, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Emiliano Zapata, Mor., MexicoRadiotherapy Service, Hospital de Alta Especialidad “Centenario de la Revolución Mexicana”, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Emiliano Zapata, Mor., MexicoCoordination of Teaching and Research. Hospital de Alta Especialidad “Centenario de la Revolución Mexicana”, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Emiliano Zapata, Mor., MexicoPurpose: To describe the institutional experience of treatment with volumetric modulated arc therapy (VMAT) in prostate cancer in the Mexican population of the Regional Hospital “Centenario de la Revolución Mexicana”, ISSSTE, Morelos. Methods: A retrospective study of patients with prostate cancer treated with radiotherapy with moderate hypofractionation at doses of 70.2Gy in 26 fractions was performed, between January 2017 and January 2021. Results: 55 patients were included in the analysis, with a median follow-up of 20.7 months, biochemical control was 100%. Acute gastrointestinal toxicity grade 1 or less occurred in 87.3% of patients, grade 2: 9.1% y grade 3 in 3.6%; acute genitourinary toxicity grade 1 or less in 90.9%, grade 2: 7.3% and grade 3: 1.8%. Regarding chronic gastrointestinal toxicity grade 1 or less, it was 95.3%, grade 2: 4.8%, There have been no grade 3 or higher cases, chronic genitourinary toxicity grade 1 or less 90.5%, grade 2: 7.1%, grade 3: 2.4%. Conclusions: Moderate hypofractionation in prostate cancer in the Mexican population presents excellent biochemical control and an adequate toxicity profile. https://www.hospitalgeneral.com/frame_esp.php?id=153Hypofractionation. Cancer. Prostate. Mexico. |
| spellingShingle | Felipe de J. Tallabs-Villafaña Oscar S. Salinas-Rosas María F. Rivera-Valaguez Palemón Gutiérrez-Balderas Verónica Andrade-Almaraz Moderate hypofractionation in prostate cancer: experience from Regional Hospital ISSSTE, Morelos Revista Médica del Hospital General de México Hypofractionation. Cancer. Prostate. Mexico. |
| title | Moderate hypofractionation in prostate cancer: experience from Regional Hospital ISSSTE, Morelos |
| title_full | Moderate hypofractionation in prostate cancer: experience from Regional Hospital ISSSTE, Morelos |
| title_fullStr | Moderate hypofractionation in prostate cancer: experience from Regional Hospital ISSSTE, Morelos |
| title_full_unstemmed | Moderate hypofractionation in prostate cancer: experience from Regional Hospital ISSSTE, Morelos |
| title_short | Moderate hypofractionation in prostate cancer: experience from Regional Hospital ISSSTE, Morelos |
| title_sort | moderate hypofractionation in prostate cancer experience from regional hospital issste morelos |
| topic | Hypofractionation. Cancer. Prostate. Mexico. |
| url | https://www.hospitalgeneral.com/frame_esp.php?id=153 |
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